Sr. Manager, Vaccines RWE Scientist

ROLE SUMMARY

The Global Scientific Affairs COVID & Flu team is on the cutting edge of evidence generation for COVID-19 & flu vaccines, therapeutics and diagnostics. Within the Global Scientific Affairs COVID & Flu team, a dedicated team of RWE Scientists reporting to the COVID & Flu Databases Team Lead develop and execute evidence generation using in-house databases to support COVID and flu vaccines, antivirals, and diagnostic assets. The Global Scientific Affairs COVID & Flu Senior Manager will deliver timely feasibility assessments, rapid real-world insights (RWI), and easy-to-understand summary reports by understanding stakeholder objectives and timelines. They will contribute to and in some cases lead the development of RWE protocols in collaboration with the cross-functional asset teams and Biostatistics to demonstrate and enhance value generation for all assets. The Senior Manager will contribute to high-impact data generation that may be used to support vaccine technical committees recommendations and authorizations, regulatory interactions/label expansions, trial design and optimization, and other real world clinical studies to further understand burden of disease and effectiveness of vaccines and therapeutics.

The Senior Manager will serve as a subject matter expert on data sources and provide guidance on the most appropriate types of data, datasets, innovative methodologies, and algorithms for a given problem, and coordinate RWE project execution with appropriate internal and partner analytic resources and tools. They will ensure the development of consistent business rules, versioning rules as care pathways evolve, standards and procedures.

The Global Scientific Affairs COVID & Flu Senior Manager will play a key role in delivering in-house RWE projects and support the development of Vaccines and Antivirals strategy to keep up with the evolving RWE landscape.

ROLE RESPONSIBILITIES

• Leads RWI for feasibility assessments, go/no-go decisions, co-design and create dashboards to inform cross-functional teams’ hypothesis generation, generate timely and detailed insights
• Collaborate with team members to build strong internal and external partnerships and act as a subject matter expert by providing expert consultations on all aspects of RWD studies and analyses, including feasibility assessment, objectives, study design, data source identification, protocol development, statistical analyses, and table shells
• Support the development of RWD and analytics capabilities and utilization, and lead in applying cutting-edge advanced analytics methodologies, analysis tools, and visualization platforms to generate novel insights and actions
• Conduct and oversee the execution of rapid RWD-based queries and studies and effectively communicate the findings and study results to internal stakeholders using tables, visualizations, short reports, and slide decks
• Contribute to and/or lead external publications including conference abstracts, poster, and manuscripts
• Define standards and processes to manage quality, consistency, usability, security, and availability of data throughout the data lifecycle; stay up to date on RWD/E best practices
• Coordinates and drives internal cross-functional teams, Biostatistics, and other colleagues to create high-quality RWE from rigorously designed protocols
• Partner with a variety of stakeholders including pipeline/asset teams (e.g., Early Clinical Development pipeline teams, Global Product Development franchise/asset teams, BU Medical affairs, HEOR, Commercial and other functions), RWE Operations Leads, Biostatistics, Digital RWD, and other colleagues as needed to collaboratively develop high-quality methods, innovative approaches, protocols, and designs
• Contribute to asset medical strategy and evidence generation planning
• Proactively identify opportunities to automate and create efficiencies, harmonize rules with other analysis teams, and load all deliverables into the Digital RWD knowledge and insights management system.
• Assess vendor due diligence for potential partnerships or new sources of data/technology as directed
• Document all requests and track progress toward project completion, create and measure quarterly ROI metrics, and ensure support to business goals

BASIC QUALIFICATIONS

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including the ability to influence and collaborate with peers, develop, and coach others, oversee, and guide the work of other colleagues to achie