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Sr. Principal, Rare Disease Strategy Director

Exact Sciences
5505 Endeavor Lane, United States, United Statesfull_timeVerifiedPosted 30 May 2025
💰 $326,000/yr($204,000/yr$326,000/yr)

About the role

Help us change lives

At Exact Sciences, we’re helping change how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you’re working to help others.

Position Overview

The Sr. Principal, Rare Disease Strategy Director works with business owners to define and lead the rare disease product lifecycle. In collaboration with commercial and strategic leaders across the enterprise, this position drives the mid- to long-term strategic development of the rare disease portfolio of products and services. In close collaboration with the Rare Disease Commercial team, the Sr. Principal, Rare Disease Strategy Director is responsible for developing and maintaining the product lifecycle and roadmaps for all rare disease offerings. This will require obtaining voice of customer (VOC) research, assessing market opportunities (including financial model), understanding customer requirements, and staying abreast of the competitive landscape in order to develop compelling business cases to invest resources to gain share of the rare disease market. This role will be responsible for understanding the broader needs of the business when defining and making product decisions.

To be successful in this role, the Sr. Principal, Rare Disease Strategy Director must develop and maintain strong internal relationships across the company, working closely with business strategy and commercial teams to understand market needs and broader portfolio strategies. In order to meet program objectives, this individual will closely collaborate with team members from Lab, R&D, Clinical, IT, Customer Experience, Operations, Finance, Regulatory, Reimbursement, Legal, Sales/Marketing, and Commercial.

This is a highly visible role that will require collaborating with and influencing varying levels of internal and external partners. This position requires a strong team-focused approach and giving high-visibility presentations to drive progress, key milestones, and alignment across the organization.

Essential Duties

Include, but are not limited to, the following:

  • Lead the definition of the rare disease portfolio of products and services and maximize its value by developing and maintaining long-term business plans including multi-generational product roadmaps and strategic P&Ls supported by robust business rationales. Collaborate with business leaders to set portfolio strategy.
  • Lead through influence to prioritize opportunities to build, cultivate, and maintain Exact Sciences’ rare disease business while establishing the business case to inform further project and resource investments.
  • In partnership with key stakeholders, oversee the successful execution of product timeline, determination of business-critical program milestones, and confirmation of inclusion and impact to program timelines. Plan aspects include, but are not limited to, evidence generation, indications and/or geographic expansion, market entry strategy, and partner collaboration opportunities.
  • Synthesize key market and clinical trends, customer needs, and competitive offerings to develop differentiated product roadmaps, new product features and functionalities, supportive solutions and services, and recommendations for investments to support product growth.
  • Provide robust financial analysis in assessing market opportunities and developing business cases for new product concepts.
  • Develop and deliver compelling presentations to convey portfolio and program strategies and/or facilitate key decisions to a broad set of stakeholders to include senior executives.
  • Contribute to multiple workstreams (i.e., financial, commercial, operational, product development, clinical) within program and special project(s) outside of direct program.
  • Delegate effectively to other functions to meet program goals and deadlines; motivate and lead teams of cross-functional resources in a matrixed organization with competing priorities, with or without direct authority or reporting relationships.
  • Build and cultivate relationships, and consistently and appropriately communicate clearly and frequently with various audiences at all levels of the organization including, but not limited to, corporate strategy team members, project team members (core and extended), functional managers, commercial organization, key opinion leaders, stakeholders, and partners.
  • Maintain morale and support employee engagement initiatives.
  • Promote an open, collaborative environment built on trust to foster positive teamwork.
  • Ability to prioritize, influence, and drive to results with a high emphasis on quality.
  • Ability

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Company

Exact Sciences

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