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Senior Product Manager
HelixUnited States - Remote, United StatesRemotefull_timeVerifiedPosted 14 Apr 2026
💰 $205,250/yr($158,000/yr – $205,250/yr)
About the role
Who We Are & What We Do
At Helix, our mission is simple: to help everyone improve their lives through their DNA.
Ready to make a real-world impact with your skills? At Helix, we're transforming healthcare by making genomics a standard of care. We partner with health systems and life science companies to accelerate the integration of genomic data into clinical practice. Join us in building a future where healthcare is personalized, proactive, and powered by genomics.
What is special about this role?
At Helix, we’re focused on improving patient lives - and this role sits at the center of that work. You’ll drive tangible improvements in a key area of the business while helping shape new, scalable ways of working in a space ready for innovation. We’re looking for someone who thrives in an AI-native organization and can blend technical depth with sharp organization and project leadership. You’ll collaborate with cross-functional teams to deliver outcomes that matter.
As a Senior Product Manager, you will:
Pluses:
Expected Interview Process:1) Manager Screen 2) Recruiter Screen 3) Final Loop 4) Offer
Expected Pay For This Role:There are 3 distinct parts to your Helix offer: 1) Base Salary 2) Annual Bonus 3) Equity
Aside from working alongside brilliant, dedicated, passionate, down-to-earth, curious, warm, and thoughtful people, we also provide great benefits:
What To Expect During Your First 90 days:
At Helix, our mission is simple: to help everyone improve their lives through their DNA.
Ready to make a real-world impact with your skills? At Helix, we're transforming healthcare by making genomics a standard of care. We partner with health systems and life science companies to accelerate the integration of genomic data into clinical practice. Join us in building a future where healthcare is personalized, proactive, and powered by genomics.
What is special about this role?
At Helix, we’re focused on improving patient lives - and this role sits at the center of that work. You’ll drive tangible improvements in a key area of the business while helping shape new, scalable ways of working in a space ready for innovation. We’re looking for someone who thrives in an AI-native organization and can blend technical depth with sharp organization and project leadership. You’ll collaborate with cross-functional teams to deliver outcomes that matter.
As a Senior Product Manager, you will:
- Define the Vision: Articulate the "why" and "what" behind efficient, AI-enabled clinical genetic interpretation, review, and sign-out, ensuring the team solves high-impact problems before a single line of code is written.
- Accelerate Innovation: Drive the AI-driven "idea-to-prototype" cycle, testing and validating multiple solutions in days, not months.
- Simplify Complexity: Distill nuanced clinical needs into elegant, scalable product requirements while maintaining a relentless focus on priority.
- Balance & Scale: Navigate high-stakes tradeoffs to deliver efficiency and scalability without ever compromising on clinical quality.
- Unify Teams: Act as the bridge between lab directors, scientists, and global engineering teams to ensure seamless product releases.
- Guardian of Trust: Oversee the health of your product area, including data privacy, security, and governance within our AI-driven solutions.
- Educational Foundation: B.S. or M.S. in Biology, Engineering, or a related technical field.
- Domain Expertise: Deep experience or knowledge of clinical genomics and variant interpretation; you understand the science behind the software.
- Proven PM Track Record: 3+ years of software product management experience in a biotech laboratory, ideally within a clinical setting.
- AI Fluency: Familiarity with integrating AI/ML models into production workflows—specifically how to leverage LLMs or generative tools to accelerate data interpretation and internal efficiencies.
- Clarity & Collaboration: Exceptional communication skills with a natural ability to translate complex technical/biological nuances into clear, actionable product needs.
- Execution Mindset: Highly organized and reliable. You thrive in ever-changing environments and have the backbone to make high-stakes, risk-based tradeoff decisions.
Pluses:
- CLIA/CAP and/or medical device experience.
- Some familiarity with SQL and relational databases, some simple programming abilities with any language
Expected Interview Process:1) Manager Screen 2) Recruiter Screen 3) Final Loop 4) Offer
Expected Pay For This Role:There are 3 distinct parts to your Helix offer: 1) Base Salary 2) Annual Bonus 3) Equity
- Expected Helix Base: $158,000 - $205,250
- Expected Helix Discretionary Annual Bonus: 10% of your annual salary
- Equity: We offer generous equity at Helix. If you receive a Helix offer your recruiter will book dedicated time with you to educate you on our equity model.
Aside from working alongside brilliant, dedicated, passionate, down-to-earth, curious, warm, and thoughtful people, we also provide great benefits:
- Comprehensive Health Insurance with Date of Hire eligibility
- Above average employer paid premium coverage
- 12 weeks Helix Paid Parental Leave option
- 401(k) with employer matching of up to 3% and 100% Vesting on the Date of Hire
- Comprehensive Well-Being Benefits
- Flexible PTO
- Remote options for many roles and a home office stipend
What To Expect During Your First 90 days:
- First 30 days: you’ll spend time learning the Helix way, completing training and onboarding for your roles, and getting introduced to your team and r
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