Sr. Director, Portfolio Management (Life Science Technology)

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

Ontada is an oncology technology and insights business dedicated to transforming the fight against cancer. Part of McKesson Corporation, a Fortune 7 company, Ontada was founded on the core belief that precise insights – delivered exactly at the point of need – can save more patients’ lives. We connect the full patient journey by combining technologies used by The US Oncology Network (USON) and other community oncology providers with real-world data and research relied on by all top 15 global life sciences companies. Our work helps accelerate innovation and power the future of cancer care.

About Us:

We specialize in real-world data (RWD) and real-world evidence (RWE) generation that accelerates life science research, clinical technologies that support community providers with precise care, and provider engagement channels that enable education and insights.

Position Overview:

We are seeking a driven and enthusiastic leader to join our team as the Senior Director of Portfolio Management. This role is responsible for the portfolio planning, financial modeling, and execution of Ontada’s technology portfolio. The Senior Director will play a pivotal role in transforming the fight against cancer and improving the lives of patients.

Reporting Structure:

This position reports to the Technology Leader and will drive technology financial and vendor management, project management, portfolio planning, and business operations. The role also supports enterprise-wide special initiatives and builds relationships with stakeholders, especially Life Science partners (Commercial, Research, Tech Product, Engineering, and QA).

Core Responsibilities:

• Translate organizational vision and strategy into actionable plans
• Lead and direct Agile planning and execution teams to deliver project deliverables on time
• Partner with Finance to ensure project financial reporting and forecasting align with organizational budgets
• Build and maintain relationships with key customers and stakeholders, ensuring delivery leadership representation
• Facilitate PMO negotiations across functions to resolve project conflicts and competing priorities
• Influence executive leadership to align around portfolio business objectives and measurable benefits
• Review and improve Agile and project management processes, communicating changes to senior leadership
• Drive financial discipline and industry best practices for demand and capacity management
• Manage relationships with strategic vendors, negotiate pricing, and drive performance metrics

Success Factors

• Deliver on promises and commitments
• Lead without authority, influence, and persuade effectively
• Demonstrate collaborative and cross-functional execution success
• Act as a people leader who nurtures collaborative partnerships
• Build trust and transparency with stakeholders
• Act as a change agent, leading continual improvement with positive energy
• Champion new ideas that contribute to organizational goals
• Align with departmental leaders to meet operational needs
• Exhibit excellent analytical and problem-solving skills
• Manage up and be transparent with decision-making processes
• Demonstrate willingness and ability to teach and learn
• Thrive in a fast-paced, ever-changing environment.

Minimum Requirements

• Degree or equivalent experience
• 13+ years of professional experience
• 6+ years of diversified leadership, planning, communication, organization, and people motivation skills.

Critical Skills

• 10+ years of experience in technology, strategic planning, and business planning
• 10+ years of experience leading a project management office
• 7+ years of experience working in Agile Methodologies
• 7+ years of experience as a project manager and/or program mana