Senior Associate Scientist

Job title: Senior Associate Scientist

• Location: Cambridge, MA

About the Job

Join our dynamic Rare Research Therapeutic Area team in Cambridge, MA, where we're dedicated to discovering and developing innovative therapies for patients suffering from rare diseases. Our multidisciplinary team combines cutting-edge science with a collaborative approach to tackle some of the most challenging diseases affecting tissues including skeletal and cardiac muscle as well as the central nervous system. We are committed to advancing the understanding of disease mechanisms and translating these insights into meaningful therapeutic solutions for patients suffering from neuromuscular and rare monogenic neurological conditions.

Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

About Sanofi:

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Main responsibilities:

• Perform experiments and studies in support of rare disease research projects and company drug discovery goals.

• Design, execute, and troubleshoot experiments in both in vivo and in vitro settings.

• Support the development of new methodologies and approaches as needed.

• Develop and maintain cell culture systems, including iPSC-derived cultures, to model rare diseases and enable drug screening and mechanism of action studies.

• Conduct animal studies using various injections routes (IV, SC, IP), necropsies, and downstream tissue processing.

• Perform cell culture techniques, qPCR, ELISA, and plate-based assays (MSD/SIMOA).

• Analyze, interpret, and present experimental results to team members and project stakeholders.

• Maintain detailed and accurate laboratory records following scientific rigor standards.

• Collaborate effectively with team members and contribute to a positive team environment.

About You:

• Bachelor's Degree in Biology, Biochemistry, Molecular Biology, or a related field plus minimum 4 years of relevant research experience in an academic or biopharmaceutical setting OR Master's Degree in Biology, Biochemistry, Molecular Biology, or a related field plus minimum 1 year of relevant research experience.

• Strong in vivo technical expertise including animal handling, various routes of administration (IV, SC, IP) and necropsy.

• Experience with various in vitro methods (i.e. qPCR, ELISA, and plate-based assays (MSD/SIMOA)).

• Knowledge of laboratory safety procedures and good laboratory practices.

Preferred:

• Strongly recommended: Proficiency in cell culture techniques, including iPSC culture systems.

• Experience with in vivo models of neuromuscular disorders and functional readouts relevant to skeletal and cardiac muscle function.

• Experience with binding assays for complex biologics (SPR, BLI/Octet)

• Experience with high-throughput screening and assay development

• Experience integrating human biology datasets (e.g., genomics, transcriptomics) into experimental workflows

• Experience with intracranial stereotaxic surgeries

• Familiarity with bioinformatics tools and data analysis software

• Previous experience in pharmaceutical or biotechnology research settings

Soft skills:

• Demonstrated ability to work in a team environment and collaborate effectively.

• Excellent documentation and record-keeping skills.

• Strong analytical and problem-solving abilities.

• Ability to prioritize and organize work to meet project deadlines

Why Choose Us

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbe