Distinguished Research Fellow / Highly Distinguished Research Fellow - Nonclinical Safety

Description

The basic purpose of this position is to provide internally and externally, the toxicological research and strategic expertise to amplify the scientific engagement of Global Nonclinical Safety (NCS) and Drug Metabolism & Pharmacokinetics (DMPK).  The main responsibility of the experienced toxicologist in this position is to contribute as a highly experienced toxicologist with a focus on discovery research and implementation of the vision and strategic objectives of Global NCS and DMPK.  The incumbent will act as internal expert in toxicology across therapeutic areas. The Highly Distinguished Research Scientist needs to have deep understanding about what is technically feasible, what will work within Research and Development that is housed within a complex, global organization.

The successful candidate will provide project teams with scientific expertise and leadership for the safety assessment of programs from early discovery, through to candidate selection and beyond.  You will contribute to the assessment and selection of novel drug targets and identify opportunities for lead optimization of novel candidate molecules using innovative molecular, cellular, and in vivo technologies and leveraging resources in Toxicological sciences.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development, and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

*** Candidate will be hired at level commensurate with experience and education****
 

Duties & Responsibilities

•    Serve as thought leader within cross-functional and cross-therapeutic area interface to R&D projects for discovery and investigative toxicology de-risking expertise.
•    Responsible for leading early safety strategy development and communication during the Research phase and designing and coordinating investigative toxicology study or research support for both small molecules and biologics.  
•    Contribute to project plans that will influence strategic direction and prioritization of global R&D projects, with impact on project and function specific goals and milestones.   
•    Determine “best practices” to seamless Research to Development transitions of nominated drug candidates to Regulatory Toxicology and R&D Drug Development Teams.
•    Serve as primary point of contact for internal (Research, Development, Medicine, Regulatory) and external regulatory interactions involving investigative toxicology de-risking of drug candidate target organ toxicities.  This includes proposing risk management options for supporting clinical development.
•    Using established internal and external networks, responsible for scoping investigative study work packages, developing study designs and their placement (internal, CRO) and execution
•    Capable of independently serving as broad subject matter expert to global senior leadership and R&D governance committees; It is expected that the incumbent will have an unimpeachable record of high level impact on a drug discovery and  development portfolio.
•    Maintain and expand an international reputation in area of expertise; Represent Boehringer Ingelheim as one of the world’s top scientific leaders in field of expertise at both internal and national/international conferences, meetings and organizations; Publish extensively on specific and general topics in drug discovery or development. Personally, and through mentorship of others, contribute to the external scientific literature on specific and general topics in drug discovery or development
•    Provide expert international scientific review requested by Senior Management on issues of R&D portfolio, technology investments and licensing opportunities; Lead global initiatives.
•    Participate and provide leadership to external industry working groups/professional societies in developing best practices and bring that knowledge to bear on internal local and international projects.
•    Consult with local and global scientific leaders regarding strategic drug discovery and development issues; Actively advocate strategic positions on industry committees and forums.  Present and defend strategic positions within Boehringer to bring continuous improvement to our scientific practices
•    Understand current nati