Sr. Research Associate-Onsite, Aliso Viejo, CA

Compensation: $80,000 - $90,000 per year. You are eligible to a Short-Term Incentive Plan with the target at 7.5% of your annual earnings, terms and conditions apply. 

Sr. Research Associate- Onsite, Aliso Viejo, CA   

The Sr. Research Associate is responsible for supporting the design, development and execution of novel assays based on Next-Generation Sequencing and emerging sequencing technologies. This role supports Ambry’s translational research initiatives, including internal and external collaborations, working with minimal supervision. This position will work as part of a multi-disciplinary team including R&D scientists, variant assessment scientists, clinical laboratory personnel, and bioinformatics specialists.

Essential Functions  

• Perform DNA/RNA isolation from biospecimens (mainly blood and saliva), NGS library preparation for short/long read sequencing, monitoring of sequencing metrics, primer design and PCR/RT-PCR.
• Contribute to the design and development of novel assays for use in translational research projects and support their transition to the clinical setting.
• Participate in drafting work instructions, standard operating procedures and other supporting documentation.
• Manage selected projects, including day to day operations, training of personnel, document review, and tracking project progress
• Other duties as assigned 

 

Qualifications 

• BS or MS degree in a life sciences field: Biology, Molecular Biology, Biochemistry or related field or equivalent work experience
• 3+ years of laboratory research experience in an academic or industrial setting
• Strong understanding of molecular biology and genetics.
• Experience with DNA/RNA extraction from biospecimen such as whole blood and saliva.
• Experience with library preparation for short or long read sequencing and subsequent analysis of sequencing metrics.
• Experience with primer design and PCRs. Experience with Microsoft Office products, especially Word, Excel and PowerPoint.
• Strong understanding and previous experience working on human genetics.
• Proficient in the following molecular biology techniques: NGS library preparation for short or long read sequencing, DNA/RNA extraction from biospecimens (blood/saliva), PCRs and analysis of electrophoretic traces.
• Ability to present organized summaries to internal stakeholders.
• Excellent organizational and record keeping skills.
• Strong willingness to learn new laboratory techniques and procedures, as well as expand your knowledge about genetic variation and its connection to inherited diseases.
• Good command of sequencing metrics interpretation.

 Preferred

• Previous experience analyzing and interpreting sequencing data is a plus.
• Previous hands-on experience with long read sequencing will be positively valued.

 

About Us:  

Ambry Genetics Corporation is a CAP-accredited and CLIA-licensed molecular genetics laboratory based in Aliso Viejo, California. We are a genetics-based healthcare company that is dedicated to open scientific exchange so we can work together to understand and treat all human disease faster. 

At Ambry, everyone is welcome. A career at Ambry Genetics is a chance to be part of a dynamic company that aims to improve health by understanding the relationships between genetics and human disease. We earned our reputation as industry leaders by responsibly introducing cutting-edge genetic testing solutions and continually sharing what we learn with the global scientific community. 

At Ambry you will be learning, challenging yourself, and having fun while collaborating with teammates through the open exchange of ideas.  Our outstanding benefits program includes medical, dental, vision, 401k with a 4% employer match, FSA, paid sick leave and generous paid time off (PTO) program. You can learn more about the benefits here. Ambry Genetics is an Equal Opportunity Employer (EOE) and we maintain a drug-free work environment. 

Our salary ranges are determined by role, level, and location. The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all US locations. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training. 

All qualified applicants will receive consideration for employment without regard to race (and traits historically associated with race, including, but n