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Senior Site Reliability Engineer

MSD
Czechiafull_timeVerifiedPosted 5 May 2026

About the role

Job Description

The Position

Join a global healthcare biopharma technology team in Prague as a Senior Site Reliability Engineer. You will own reliability, scalability, and security for critical platforms and applications that support medicines, vaccines, and animal health products worldwide. This role combines hands-on engineering with strategic leadership: you’ll drive modernization, shape operational best practices, mentor engineers, and collaborate across products and regions to deliver resilient, high-performing systems.


What will you do?

  • Lead reliability efforts: define and own SLOs/SLIs, error budgets, availability goals, and improvement plans for services under your scope.
  • Design and implement robust, scalable architectures and automation that minimize operational toil and support rapid delivery.
  • Build and maintain IaC, CI/CD pipelines, and automated testing to ensure consistent, auditable deployments.
  • Drive observability and proactive monitoring: implement metrics, logging, tracing, and alerting that enable data-driven reliability improvements.
  • Lead incident response for complex issues, coordinate cross-team resolution, conduct blameless postmortems, and drive preventative actions.
  • Establish and codify operational frameworks, runbooks, and standard methodologies to raise operational maturity across teams.
  • Coach and mentor SRE and DevOps engineers; foster knowledge sharing and create a pipeline of technical leaders.
  • Partner with product engineering, security, platform, and vendor teams to align technology roadmaps, compliance, and lifecycle management (patching, upgrades).
  • Perform capacity planning, performance analysis, and troubleshooting for distributed systems and cloud platforms.
  • Produce and maintain technical documentation, architecture diagrams, installation qualification/validation artifacts, and compliance evidence when required.


Qualifications, Skills & Experience Required

  • BSc in Computer Science, IT, Engineering, or equivalent experience; advanced degree a plus.
  • 5+ years of hands-on experience in SRE, Platform, or DevOps engineering with proven ownership of reliability for production systems.
  • Deep experience with cloud platforms (AWS preferred; Azure/GCP experience valuable) and cloud-native services.
  • Strong skills with IaC (Terraform, CloudFormation, or similar), Git-based workflows, and mature CI/CD pipelines.
  • Demonstrated experience defining and operating SLOs, SLIs, SLAs, and error budget processes.
  • Proficiency with observability tooling (Prometheus, Grafana, ELK/EFK, OpenTelemetry, distributed tracing).
  • Solid programming/scripting skills (Python, Go, Bash, PowerShell, or similar) and experience building automation and tooling.
  • Strong knowledge of networking (VPCs, VPNs, load balancing, firewalls) and cloud security best practices and compliance frameworks.
  • Experience with platform engineering patterns, multi-tenant platforms, and managing analytics or data platforms is a plus.
  • Familiarity with Conversational BI tools, Power Platform, and emerging LLM/Copilot concepts.
  • Excellent problem-solving, communication, and stakeholder-management skills; experience working with global, cross-functional teams.
  • Relevant certifications (AWS Professional, Kubernetes, etc.) are a plus.

Nice to have

  • Prior experience in regulated industries (pharma/healthcare) with understanding of validation and compliance requirements.
  • Experience designing or operating cloud-native analytics platforms and multi-tenant services.
  • Leadership experience in building and scaling engineering teams or center-of-excellence functions.

What we offer

  • Exciting work in a great team, global projects, international environment 
  • Opportunity to learn and grow professionally within the company globally 
  • Hybrid working model, flexible role pattern (e.g., even 80% full-time is possible in justified cases) 
  • Pension and health insurance contributions 
  • Internal reward system plus referral programme 
  • 5 weeks annual leave, 5 sick days, 15 days of certified sick leave paid above statutory requirements annually, 40 paid hours annually for volunteering activities, 12 weeks of parental co

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Company

MSD

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