Senior Scientist I/II, In Vivo Pharmacology (Echocardiography) – CVM

Band

Level 3

 

Job Description Summary

We are seeking a highly motivated scientist specialized in echocardiography to join our in vivo pharmacology team in the Cardiovascular and Metabolic (CVM) Disease Area at the Novartis BioMedical Research (BR) facility located in Cambridge, MA. Cardiometabolic disease is the leading cause of death worldwide, taking an estimated 17.9 million lives each year. Our team is dedicated to the creation and development of innovative medicines to change this alarming statistic. We conceive, develop, validate, and employ pharmacological tools to evaluate the efficacy and safety of novel cardiometabolic drug candidates.

As an experienced and skilled lab-based echocardiographer, you will work both independently and collaboratively in an inter-disciplinary setting to execute experiments in preclinical models of cardiovascular disease. You will perform multi-mode echocardiography including strain by speckle tracking and Doppler imaging for heart systolic function and diastolic function. You will collect, analyze, and interpret echo images, and report cardiac structural and functional data in both written study reports and at team meetings. You will support drug discovery for heart failure and arrhythmia therapeutics by participating in pharmacodynamic/pharmacokinetic (PK/PD) and efficacy studies, while broadening your knowledge in the non-invasive imaging field.

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This position will be located at Cambridge and will not have the ability to be located remotely

 

Job Description

Key responsibilities:

• Independently design, execute, analyze, and document in vivo echocardiographic experiments in heart failure and/or arrhythmia animal models.
• Employ good laboratory, data recording and data documentation practices.
• Establish new imaging techniques and approaches to support heart failure or arrhythmia studies.
• Support drug discovery projects with PK/PD studies.
• Collaborate effectively while working in a matrixed environment.
• Present results in lab and department meetings.
• Assist in the completion of research reports to support regulatory filings.

Minimum role requirements

• Bachelors or Masters in pharmacology, physiology, or other life sciences area
• 3-5+ years of relevant experience in rodent echocardiography.
• Experience in handling, dosing, and phenotyping animal models of disease, ideally with an emphasis in heart failure, arrhythmia or cardiorenal disease, experience with non-rodent models would be a bonus
• Drug discovery experience desirable.
• Experience in working with a multidisciplinary team of scientists.
• Basic knowledge of statistics and experience with common statistical software for biomedical research.
• Proficiency with Microsoft Office (Word, Excel and PowerPoint).
• Strong written, oral and record keeping skills.
   

The salary for this position is expected to range between Senior Scientist I: $85,400- $158,600/year | Senior Scientist II: $93,800-$174,00/year.

The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

To learn more about the culture, rewards and benefits we offer our people click here.

 

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

 

Accessibility and reasonable accommodations

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