Principal Scientist/Senior Principal Scientist, Analytical Chemistry

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Our Chemical Process Development group is a team of organic chemists, analytical chemists, and chemical engineers working together to design novel syntheses from raw materials to supply new medicines to patients. Our scientists focus on developing safe, economical, sustainable, and robust processes to support clinical trials and the launch of new medicines across various drug modalities including small molecules, peptides, oligonucleotides, and antibody drug conjugates. The work is driven by innovative science, data-driven decision-making, and collaborative teamwork. The scientific knowledge package from the manufacturing process, design parameters, and control strategies enables regulatory filings to bring these novel medicines to patients worldwide.

Position Summary:

We are seeking an experienced leader with strong analytical technical skills and a passion for strategic project leadership, mentoring others and driving technical innovation to solve challenging problems.  This role will provide analytical subject matter expertise and analytical leadership within process development teams consisting of organic chemists, chemical engineers, analytical scientists to support an increasingly complex Portfolio of small molecules and milla-molecular (ADCs, peptides, oligonucleotides) drug candidates from phase 1 to commercialization. The successful candidate is expected to manage multiple projects, provide strategic leadership, collaborate with stakeholders to move the portfolio through development to regulatory submissions.

Role & Responsibilities:

• Coordinating the analytical activities in alignment with other project leads (process chemistry, engineering, technology and supply) to enable process innovation and invention.
• Developing phase appropriate analytical control strategies and coordinating method development, validation and transfer activities to support process development, internal/external campaigns, compliance needs and regulatory submissions.
• Providing fit-for-purpose analytical methods and analyses which provide key insights and process knowledge for scale-up and process optimization studies for projects within the portfolio.
• Appropriate resource planning and activity coordination of internal and external work packages.
• Partnering with other Analytical Functions across the Product Development and Commercial organizations to integrate/align analytical strategies, build development knowledge, collect necessary analytical data, and significantly influence specification setting and IND/NDA submission content. 
• Capability to adapt and grow within a dynamic environment including both internally and externally based development activities. Collaborate with SMEs / project team on innovative analytical approaches to solve challenging problems. Leverage technical expertise to drive problem solving and knowledge gathering.
• Seeking opportunities to influence/mentor other scientists in the team, the wider analytical community or the external community (through consortia / guidance and publications) through lessons learned and workflow/ practice enhancements.
• Accountable for identifying opportunities and/or implementing solutions to improve efficiency, productivity and quality across various areas including:  continuous processing, applying automation, screening, smart technology and vendor interactions.

The successful candidate is expected to significantly impact the advancement of the Portfolio through their strong analytical technical skills, strategic leadership and capability to manage mult