Associate Director, Clinical Outcomes Assessment - Evinova

Evinova is a health-tech business, accelerating the delivery of better health outcomes by propelling the life sciences sector forward in digital health, from the inside. Through our application of science-based expertise, evidence-led rigour, and human insight, our digital solutions are deliberately designed so that everyone can reach better health outcomes together. Evinova is a health-tech business within the AstraZeneca Group.

We’re building out a best-in-class Measurement Science team to support the R&D portfolio as well as digital therapeutics, which will be part of the future of measurement science and analytics to support novel endpoints/interventions. 

Digital health, the point at which healthcare, technology, data and analytics converge, is the subject of phenomenal promise, with the World Health Organisation believing it has the potential to improve health for everyone. At AstraZeneca, we’ve been working hard to make this a reality, with the years of experience we have accumulated enabling us to now embed digital health at scale across R&D. To achieve our goal of improving patient experience and outcomes AstraZeneca has Digital Health as one of the top 4 strategic priorities for the company, details on digital health strategy can be found here. Oncology is the largest therapeutic area within AstraZeneca and second highest cause of death globally, with AstraZeneca’s ambition to eliminate cancer as a cause of death.

An Associate Director in the COA Measurement Science, Centre of Excellence should have experience in the use of clinical outcomes assessments (COA) such as traditional survey-like instruments using rating or ranking scales and novel sensor/wearable data capture instruments to inform identification and/or evaluation of symptoms, function, health-related quality of life, or other patient-centric concept of clinical benefit throughout the oncology drug development lifecycle.  With supervision, the Associate Director will be responsible for providing qualitative and quantitative measurement support for the development and execution of patient-centered measurement strategy and dissemination of its findings to key collaborators, such as R&D global and/or cross-functional teams, regulators, payers, healthcare professionals and most importantly patients in support of more efficient identification of treatment benefits vs harms in Oncology.  This includes but is not limited to: identification and exploration of unmet measurement need by conducting literature reviews and/or qualitative research studies, description of context of use (e.g., selection of responders for fit-for-purpose use of Patient-Reported Outcomes, Observer-Reported Outcomes, Clinician-Reported Outcomes, or Performance Outcome assessments), selection of data collection strategy and implementation in clinical research or real world setting, collaboration for data analyses and interpretation and audience-adapted publications.  The Associate Director will be encouraged to partner with scientific leaders within the organization to identify specific areas of interest for professional development, with the ultimate goal of becoming a recognized leader in the COA/digital health field. 

What you’ll do

As the Associate Director, you will play a pivotal role in channelling our scientific capabilities to make a positive impact on changing patients’ lives through the following:

• Contribute to qualitative and quantitative research to generate evidence of patients' experience with treatment throughout the oncology drug development lifecycle (e.g., identification and exploration of unmet measurement need, endpoints capturing symptoms, function, or quality of life evolution overtime to inform disease progression or tolerability) including study design/oversight and data collection
• Responsible for project management of functional service provider(s) for qualitative and quantitative research to inform development of conceptual disease-models and related endpoints to address measurement gap to inform the patients' experience with treatment.
• With minimal supervision, contribute to the exploration of COA in clinical research to inform clinical benefit evaluation of oncology treatment, including: measurement performance evaluation of symptom(s), function and health-related quality of life instruments,  definition or development of novel COA endpoints to address evidence needs from key collaborators,  and data collection to inform decision making related to the inclusion of COA endpoints and findings in major deliverables such as: clinical development plans, study protocols, and strategic and operational reports.
• With support from line management, partner with scientific leaders within Digital Health Oncology to identify, pursue, and develop indep