Sr. Manager, Immunology Flow Cytometry

The Role

Moderna is seeking a talented and motivated cytometrist to head a highly dynamic flow cytometry unit to support discovery and translational research across multiple therapeutic areas to facilitate the advancement of Moderna’s mRNA technology platform. This lab-facing position is based at the Moderna Cambridge site, within the Cellular Immunology and Technology Innovation section, Department of Infectious Diseases. The applicant’s primary role will be to implement cytometry infrastructure and governance, user-training and consulting, instrument quality control, panel development, and assay execution with analysis of preclinical and clinical samples. The individual in this role will investigate immune-related molecular and cellular mechanisms of vaccines. He/she/they should be passionate about flow cytometry and possess substantial hands-on experience in best practices, assay troubleshooting, and will have the ability to work in a highly collaborative, dynamic, and interdisciplinary environment.

Here’s What You’ll Do

• Ensure smooth operation of a diverse, state-of-the-art, and high-output flow cytometry core facility

• Equipment and reagent quality control tracking

• Multi-color panel development, experimentation, analyses and reporting to subject matter experts, cross-functional key stakeholders, and senior leadership

• Cell sorting for downstream applications, including multi-omic molecular and cellular profiling, and antibody discovery campaigns

• Foster productive relationships across multiple therapeutic areas in Research, supporting/educating users on tailoring fit-for-purpose assays and workflows to meet program/project goals and objectives

• Support discovery and translational research to facilitate expansion of Moderna’s vaccine/therapeutic portfolio and mRNA/LNP platform technology.

• Manage direct reports to efficiently execute core competencies of flow cytometry facility

• Requirements include regular attendance in Cambridge Monday-Friday, with heavy lab presence, occasional on-site attendance outside of core hours 8 AM – 6 PM, ability to lift materials up to 35 lbs

Here’s What You’ll Need (Minimum Qualifications)

• BS and 5+ years experience contributing to an established flow cytometry-intensive team in with an outstanding background in cellular immunology research

• Comprehensive understanding of cellular biomarkers for dissecting heterogeneity in a wide variety of tissues, species, and diseases

• Demonstrable history of performing high-quality flow cytometry research, possessing in-depth understanding of instrumentation, including practical experience in assay optimization/troubleshooting for a wide-range of analytical and cell sorting applications

• Excellent communication and technical skills, and ability to work efficiently in a multicultural highly dynamic and matrixed environment

Here’s What You’ll Bring to the Table (Preferred Qualifications)

• Expert in high-dimensional panel development, full-spectrum cytometry (Cytek Biosciences), and working knowledge across a broad array of cytometry technologies/analytics is highly desirable. Experience in single-cell multi-omics approaches and instrumentation, including 10x genomics and CITE-Seq is a plus. Experience in image flow cytometry, histo-cytometry, workflow automation, and/or computational/unsupervised dimensionality reduction data visualization methods of large datasets is a plus.

• Previous experience operating and/or leading high-performing, agile flow cytometry core facilities, include direct report management experience is highly desired.

• A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative.

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

• Highly competitive and inclusive medical, dental and vision coverage options
• Flexible Spending Accounts for medical expenses and dependent care expenses
• Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
• Family care benefits, including subsidized back-up care options and on-demand tutoring
• Free premium access to fitness, nutrition, and mindfulness classes 
• Exclusive preferred pricing on Peloton fitness equipment
• Adoption and family-planning benefits
• Dedicated care coordination support for our LGBTQ+ community
• Generous paid time off, including:
  •    Vacation, sick time and holidays
  •    Volunteer time to participate within your community
  •    Discretionary year-end shutdown
  •    Paid sabbatical after 5 years; every 3 years there