Nuclear Medicine Technologist, Thernostics and Radiation Science

Fusion Pharmaceuticals, a member of the AstraZeneca Group, is a clinical-stage oncology company focused on developing next-generation radioconjugates (RCs) as precision medicines. Fusion connects alpha particle emitting isotopes to various targeting molecules to selectively deliver the alpha emitting payloads to tumors. Fusion’s clinical portfolio includes but is not limited to: FPI-2265 targeting prostate specific membrane antigen (PSMA) for metastatic castration resistant prostate cancer currently in a Phase 2 trial; FPI-1434 targeting insulin-like growth factor 1 receptor currently in a Phase 1 trial; and FPI-2068, a bispecific IgG-based EGFR cMET targeted radioconjugate currently in a Phase 1 trial.

Fusion has multiple other pipeline programs that will soon be entering into early FIH trials. In addition, Fusion is pursuing combination programs between RCs and other therapeutic modalities including DNA Damage Response Inhibitors (DDRis) and immune-oncology agents. To support execution for these programs, Fusion has a fully operational Good Manufacturing Practice (GMP) compliant state-of-the-art radioconjugate manufacturing facility to meet supply demand for our growing pipeline of RCs. 

Candidates for the Scientist, Theranostics role need to work on a hybrid basis out of our Boston, Massachusetts office. 

Responsibilities 

• Assist in the development of, and adherence to, imaging trial documents (e.g., Image Review Charter, Imaging Manual, Data Transmittal Forms, and Dosimetry Manuals).  

• Provide subject matter expertise to internal and external stakeholders in matters of image acquisition, storage, review, and processing.  

• Maintain an archive of imaging related data for ongoing and completed trials.  

• Collaborate with clinical operations in the oversight, conduct and management of imaging-related aspects of clinical studies in accordance with the clinical protocol, study manuals and plans, and timelines while ensuring quality in accordance with GCP and ICH guidelines.  

• Assist with the management of in-house processing of image data and internal dosimetry efforts to support ongoing research and multi-disciplinary department and company initiatives.  

• Provide support for clinical data review; assist in generation of clinical research reports and presentations including abstracts, posters, and publications.  

• Provide support to clinical site staff and investigators pertaining to preparation, administration, and waste management of imaging and therapeutic radiopharmaceuticals.  

• Respond to radiation safety questions and concerns regarding the use of diagnostic and therapeutic radiopharmaceuticals and precautions.  

• Have a working knowledge and understanding of modern electronic infrastructures relevant to radiological imaging such as DICOM, PACS, IHE models, image processing and advanced visualization.  

• Willingness to travel when needed (5-10%) 

Qualifications 

• The candidate should have a Bachelor of Science degree with a life science focus from an accredited educational institution and NMTCB/ARRT(N) certification in nuclear medicine or e