Modeling & Simulations Engineering Senior Scientist

Job Description

General Summary: 

The M&S Engineering Senior Scientist will develop physical, mathematical and computational models based on structural mechanics, fluid dynamics, and thermodynamics. The incumbent will generate mechanistic and data-driven insights that will accelerate design, manufacturing, and failure mode analysis of an immunoprotective device solution for cell and gene therapies. 

 

Key Duties and Responsibilities: 

• Apply engineering skills, data analysis, computational modeling to optimize design and fabirication of an implantable combination product.

• Manage complete modeling project operations entailing requirement gathering, scoping, input data requirements, problem solving, verification, validation, and documentation. 

• Initiate & lead brainstorming and ideation sessions to develop device design and manufacturing concepts.

• Develop experimental designs in collaboration with other engineers and scientists. 

• Work with Device Fabrication team on assessing the manufacturability of the device designs via rapid prototyping methods and accelerate design ideation phase via fit-for-purpose models and simulations. 

• Collaborate with clinical and preclinical teams to understand anatomical constraints and eliminate device mechanical failure modes. 

• Effectively communicate modeling results and findings at multiple levels in the organization through project status meetings, presentations, and reports. 

Knowledge and Skills: 

• Expertise in the mechanics and thermodynamics of polymers including plastics, hydrogels, and rubber materials.

• Experience in multiphysics modeling of phase transition in engineering and biological materials

• Familiarity with implantable medical devices, and understanding of tissue mechanics. 

• Expertise in Computer Aided Design (e.g. SolidWorks), Finite Element Method (e.g. ANSYS Mechanical, or COMSOL), Finite Volumes Method (e.g. Fluent, or Star-CCM+), and familiarity with scientific machine learning. 

• Excellent knowledge of mechanical engineering design concepts, ASTM standards, design control, and tolerance analysis with hands-on experience with materials test systems (i.e. Instron) 

• Quickly adapt to evolving priorities, rapidly acquire new skills, and stay informed on new methods and approaches. 

• Strong verbal and written communications skills with ability to effectively communicate at multiple levels in the organization through project status meetings, presentations, and reports. 

Education and Experience: 

Bachelor's degree and 8+ years of experience or a Master's degree and 5+ years of experience or a PhD and 2-5 years of experience, or the equivalent combination of education and experience. 

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as: 
1.    Hybrid: work remotely up to two days per week; or select
2.    On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United St