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Senior Director, Global Health Economics Outcomes Research (HEOR)
PTC Therapeutics, Inc.United Statesfull_timeVerifiedPosted 2 Jun 2026
💰 $310,800/yr($246,900/yr – $310,800/yr)
About the role
PTC Therapeutics is a global commercial biopharmaceutical company. For over 25 years our team has been deeply committed to a unified purpose: Extending life’s moments for children and adults living with a rare disease.
At PTC, we cultivate an inclusive culture where everyone feels valued, respected, and empowered. We welcome candidates from all backgrounds to join our team, fostering a strong sense of belonging.
Visit our website to learn more about our company and culture!
Site: www.ptcbio.com
Job Description Summary:
The Senior Director, Global HEOR, is responsible for the development and execution of high-quality HEOR strategic activities to support optimal reimbursement and market access, with a focus on delivering robust evidence demonstrating the value of the product and successfully impacting business objectivesJob Description:
Responsibilities:
- Design execute strategies that demonstrate product value to Health Technology Agencies, and support commercialization, including reimbursement and pricing activities
- Work in collaboration with Market Access and Commercial Leads to identify payer evidence needs across the products´ life cycle.
- Partner with Global Medical Affairs and Development teams to provide evidence generation needs and payer requirements into clinical trial and
- protocols.
- Partner with Biostatistics regarding Statistical Plans, subgroup analysis, and clinical protocol designs to reflect payer requirements
- Monitor and capture global HTA and evidence requirements to inform the internal organization.
- Lead global economic model development, coordinate country adaptations in line with country teams and external vendors.
- Develop process and quality review of country HTA submissions, especially economic modeling (cost-effectiveness, budget impact models).
- Collaboration with Global Market Access to develop value-based pricing models for cutting-edge assets and rare disease products.
- Lead various database analyses such as patient registry data, epidemiologic research, and others
- Lead health economic-related publication and communication strategies, including presenting at external conferences.
- Assist Marketing/Market Access in the development of training materials and modules related to health economic messages.
- Where appropriate, undertake in-house economic studies and related activities such as literature reviews and modeling.
- Performs all PTC business in accordance with all regulations and PTC policies and procedures.
Qualifications:
- Ph.D., Pharm.D., M.P.H., M.S or M.D. in Public Health, Health Economics, Epidemiology, Medicine, Pharmacoeconomics, Pharmacy Administration, Pharmacy or related scientific field
- Minimum 10 years of experience in health economics and/or outcomes research in the pharmaceutical or biotechnology industry.
- Proven ability to develop health economic strategies in support of commercial programs. Product launch experience preferred.
- Experience interacting with payers or payer agencies
- Good understanding of the global reimbursement environment is required, with building global/regional health economics and pricing dossiers and/or reimbursement dossiers submitted to managed care or national authorities.
- Superior communication skills, together with familiarity with basic statistical concepts, are preferred.
- Well-developed interpersonal skills to work well in a cross-functional team as a constructive and effective member.
- Possesses strong business acumen.
- Agile, competent, and with demonstrated ability to influence.
- Leadership qualities essential to operate in a shared service model with global stakeholders.
- Demonstrated ability to take initiative, be a self-starter and establish successful internal work relationships with co-workers and client groups.
- Ability to work independently and collaboratively, as required, in a fast-paced, matrixed, team environment consisting of internal and external team members.
- Knowledge of common market practices in the life sciences industry.
- Excellent verbal and written communication skills and ability to create and give presentations to groups of all sizes.
- Strong work ethic and sense of professionalism and discretion, demonstrating accountability, integrity, and respect for confidentiality.
- Proficiency with Microsoft Office.
- Analytical thinker with excellent problem-solving skills and the ability to adapt to changing priorities and deadlines.
- Excellent planning, organization, and time management skills, including the ability t
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