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Senior Director, Global Health Economics Outcomes Research (HEOR)

PTC Therapeutics, Inc.
United Statesfull_timeVerifiedPosted 2 Jun 2026
💰 $310,800/yr($246,900/yr$310,800/yr)

About the role

PTC Therapeutics is a global commercial biopharmaceutical company. For over 25 years our team has been deeply committed to a unified purpose: Extending life’s moments for children and adults living with a rare disease.

At PTC, we cultivate an inclusive culture where everyone feels valued, respected, and empowered. We welcome candidates from all backgrounds to join our team, fostering a strong sense of belonging.

Visit our website to learn more about our company and culture!
Site: www.ptcbio.com

Job Description Summary:

The Senior Director, Global HEOR, is responsible for the development and execution of high-quality HEOR strategic activities to support optimal reimbursement and market access, with a focus on delivering robust evidence demonstrating the value of the product and successfully impacting business objectives

Job Description:

Responsibilities:

  • Design execute strategies that demonstrate product value to Health Technology Agencies, and support commercialization, including reimbursement and pricing activities
  • Work in collaboration with Market Access and Commercial Leads to identify payer evidence needs across the products´ life cycle.
  • Partner with Global Medical Affairs and Development teams to provide evidence generation needs and payer requirements into clinical trial and
  • protocols.
  • Partner with Biostatistics regarding Statistical Plans, subgroup analysis, and clinical protocol designs to reflect payer requirements
  • Monitor and capture global HTA and evidence requirements to inform the internal organization.
  • Lead global economic model development, coordinate country adaptations in line with country teams and external vendors.
  • Develop process and quality review of country HTA submissions, especially economic modeling (cost-effectiveness, budget impact models).
  • Collaboration with Global Market Access to develop value-based pricing models for cutting-edge assets and rare disease products.
  • Lead various database analyses such as patient registry data, epidemiologic research, and others
  • Lead health economic-related publication and communication strategies, including presenting at external conferences.
  • Assist Marketing/Market Access in the development of training materials and modules related to health economic messages.
  • Where appropriate, undertake in-house economic studies and related activities such as literature reviews and modeling.
  • Performs all PTC business in accordance with all regulations and PTC policies and procedures.

Qualifications:

  • Ph.D., Pharm.D., M.P.H., M.S or M.D. in Public Health, Health Economics, Epidemiology, Medicine, Pharmacoeconomics, Pharmacy Administration, Pharmacy or related scientific field
  • Minimum 10 years of experience in health economics and/or outcomes research in the pharmaceutical or biotechnology industry.
  • Proven ability to develop health economic strategies in support of commercial programs.  Product launch experience preferred.
  • Experience interacting with payers or payer agencies
  • Good understanding of the global reimbursement environment is required, with building global/regional health economics and pricing dossiers and/or reimbursement dossiers submitted to managed care or national authorities.
  • Superior communication skills, together with familiarity with basic statistical concepts, are preferred.
  • Well-developed interpersonal skills to work well in a cross-functional team as a constructive and effective member.
  • Possesses strong business acumen.
  • Agile, competent, and with demonstrated ability to influence.
  • Leadership qualities essential to operate in a shared service model with global stakeholders.
  • Demonstrated ability to take initiative, be a self-starter and establish successful internal work relationships with co-workers and client groups.
  • Ability to work independently and collaboratively, as required, in a fast-paced, matrixed, team environment consisting of internal and external team members.
  • Knowledge of common market practices in the life sciences industry.
  • Excellent verbal and written communication skills and ability to create and give presentations to groups of all sizes.
  • Strong work ethic and sense of professionalism and discretion, demonstrating accountability, integrity, and respect for confidentiality.
  • Proficiency with Microsoft Office.
  • Analytical thinker with excellent problem-solving skills and the ability to adapt to changing priorities and deadlines.
  • Excellent planning, organization, and time management skills, including the ability t

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Company

PTC Therapeutics, Inc.

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