Research Associate II/ Sr. Research Associate I, Molecular Engineering

Scribe Therapeutics is a molecular engineering company focused on creating best-in-
class in vivo therapies that permanently treat the underlying cause of disease. Founded

by CRISPR inventors and leading molecular engineers Benjamin Oakes, Brett Staahl,
David Savage, and Jennifer Doudna, Scribe is overcoming the limitations of current
genome editing technologies by developing custom engineered enzymes and delivery

modalities as part of a proprietary, evergreen CRISPR by DesignTM platform for CRISPR-
based genetic medicine.

We are seeking a highly creative, passionate, and motivated individual to join us in our
quest to develop the next generation of CRISPR-based therapeutics. The current role is
for a Senior Research Associate, Molecular Engineering to join our team and advance
our platform. The candidate should have a passion for working collaboratively with
biologists and bioengineers to enable building the necessary tools for meeting the new
frontier of CRISPR-based therapeutics. Additionally, the candidate would bring expertise
in molecular biology and cell culture.

The candidate will have numerous opportunities for professional growth in a rapidly
growing biotechnology start-up, which includes growing into a leadership role of
increasing responsibilities and the ability to publish highly impactful work in peer
reviewed journals.

Key Responsibilities:
● Work closely with the engineering team to clone and characterize CRISPR
molecules to advance activity, specificity, and novel functionality
● Execute the necessary molecular biology, tissue culture, biological assays, and
related data processing and analysis
● Help the team design and execute hypothesis-driven and properly controlled
studies, analyze data with rigorous statistics, and write up publication quality
reports

● Effectively collaborate with members within a fully integrated team to facilitate
execution on projects within established timelines
● Effectively present data and communicate research plans and timelines to the
core team
● Foster a driven, fast-paced, dynamic, and fun environment in which to do
rigorous science

Required Skills and Background:
● A BS/BA in Bioengineering, Cell or Molecular Biology, Synthetic Biology, or related
discipline
● 3-5+ years wet lab research experience & previous industry experience required
● High level of proficiency in mammalian cell culture (transfection, gDNA harvest,
cell line generation), flow cytometry, and high throughput workflows
● High level of proficiency in design and execution of molecular cloning workflows,
including Gibson assembly, Golden Gate assembly, and site-directed mutagenesis
techniques
● Experience with NGS library prep
● Exemplify our values of integrity, creativity, drive and pragmatism
● Excellent communication and organizational skills
● Ability to work both independently and collaboratively in a fast-paced,
interdisciplinary research team

Preferred Skills and Background:
● Post graduate studies are a plus
● Experience with CRISPR-Cas gene editing systems and delivery technology desired
● Experience with library generation & pooled screening techniques
● Familiarity with protein or RNA structure and engineering approaches

Salary will be commensurate with experience. We will provide an intellectually
stimulating, collegial and fast-paced environment. If you are ready to engineer the
future of therapeutics, then we are excited to hear from you! Visit us at
www.scribetx.com.

We are committed to creating a diverse environment and are proud to be an equal
opportunity employer. All qualified applicants will receive consideration for
employment without regard to race, color, religion, gender, gender identity or
expression, sexual orientation, national origin, disability, age, or veteran status.

At the time of posting, the base pay wage range for this role will depend on level.  The offered pay range will depend on internal equity and the candidate’s relevant skills, experience, qualifications, training, and market data.  Additional incentives are provided as part of the complete package in addition to comprehensive medical and other benefits.