contract - Sr. Research Associate, Analytical Development

Role: Be Biopharma is seeking a candidate for the Process Analytics sub-team in the Analytical Development (AD) department. AD is responsible for characterizing the B cell medicine, the expressed protein, and process impurities. There are three significant responsibilities within the Process Analytics sub-team, executing analytical methods for characterizing the manufacturing process, development of in-process and fit for purpose methods, and capturing data in an electronic laboratory notebooks (ELN) and reports for traceability. Roles and responsibilities will be given based on experience and knowledge in the cell therapy analytical development field. This is an excellent opportunity for career growth as you would interact with various program teams and be involved in learning and executing a diverse number of methods.

Responsibilities:

• Executing, implementing, and documenting, routine characterization and release assays for identity, purity, strength, and potency (techniques may include cell counting, flow cytometry, ELISA/MSD, ddPCR, etc).
• Develop and optimize in-process and fit for purpose methods for characterization of B cell medicine, the expressed protein, cel health, process impurities and metabolites.
• Support Analytical Development and Process Analytics activities.
• Accurately capture data in a timely manner, conduct trending data analysis and perform routine instrument maintenance. 
• Manage analytical reagents inventory, including reference standard materials as per regulatory standards.
• Be an active and strong team player contributing to group priorities and deliverables.

Experience, Education, Specialized Knowledge, and Skills:

• BS or MS in Chemical Engineering, Biology, Analytical Chemistry, Biochemistry, Cell & Molecular Biology, or related discipline with 0-2 years of industry experience.
• Hands-on experience with flow cytometry is highly preferred but not limited to other assays including ELISA, MSD, PCR, qPCR, and ddPCR.
• Demonstrated understanding of analytical method development and optimization in compliance with ICH guidelines preferred but not required.
• Experience documenting procedural steps and results within an ELN system.
• Excellent communication and presentation skills with the proven ability to solve complex problems and to work effectively as a member of a multidisciplinary team, detail oriented, and critical thinker.
• Ability to use literature to design proof of concept studies.

About Be Biopharma

Be Biopharma (“Be Bio”) is pioneering Engineered B Cell Medicines (BCM) to dramatically improve patients’ lives who are living with cancer, rare diseases and other serious conditions. With eyes locked on the patient, our team of purpose-driven scientists, technologists, manufacturing experts and business builders collaborate to create a bold new class of cell therapies. Be Bio was founded in October 2020 by Longwood Fund and B cell engineering pioneers David Rawlings, M.D., and Richard James, Ph.D. from Seattle Children’s Research Institute. Be Bio is backed by ARCH Venture Partners, Atlas Venture, RA Capital Management, Alta Partners, Longwood Fund, Bristol Myers Squibb and Takeda Ventures. Since our founding, Be Bio’s investors have committed over $180 million to enable the Company to re-imagine medicine based on the power of B cell therapy. For more information, please visit us at Be.Bio and our LinkedIn page.

Culture

The beating heart of Be Bio is our People and together we are building a culture driven by purpose, passion, and that’s full of character.  We are “all-in” as we align ourselves with patients who need our medicines, and we embrace the highest standards of transparency, excellence, candor, collaboration, and team-based science with a shared ownership of company milestones and successes. 

Our commitment to our team members is to deliver a compelling, dynamic work experience that enables them to continually stretch, grow, and learn, that enriches their lives, that fosters a sense of belonging and community, and that goes above and beyond to support them in big, meaningful ways in both their personal and professional lives.  Be Bio is a team that works hard, plays hard, and supports each other on our shared journey to get transformative medicines to patients who need them.