Postdoctoral Scholar

Description

Title: Postdoctoral Scholar

Salary Range: $62,000 - $65,000

Department: Biochemistry

Institute: School of Medicine, Case Western Reserve University

Supervisor: Wenjian Gan, Associate Professor

 

Job Summary

Postdoctoral fellow to work full-time on understanding the functions of protein post-translational

modifications in human cancers. The research will focus on the regulatory mechanisms and

physiological functions of arginine methylation in genomic instability, metabolism, cell signaling,

and cancer progression, as well as exploring druggable targets for cancer therapy. Studies will

use a range of complementary methods including biochemistry, molecular and cellular biology,

functional cell-based assays and mouse genetic models. More details can be found in lab

website https://www.wenjianganlab.com/

 

Job Duties

1. Using molecular biology and cell culture models to dissect questions related to arginine

methylation. These duties include DNA/RNA purification, plasmid construction, PCR, RT-

qPCR, cell culture, transfection, protein exaction, immunoprecipitation, western blot, cell

proliferation, and colony formation.

2. Using genetic mouse models to study the role of arginine methylation in cancer progression

and metastasis. These duties include genotyping of mice, mice maintenance, mice

breeding, drug treatment studies, monitoring for cancer development.

3. Collaborates with the PI to prepare manuscripts and grants. Duties include preparing figures

based on data collected, writing manuscripts and grants with the PI and senior team

members, presenting current work in research in progress seminars, attending departmental

seminars and participating in journal clubs.

4. Collaborates with other lab members to maintain the laboratory, including making buffers,

equipment maintenance, cleanup of lab areas, monitoring usage and deliver of lab supplies.

Qualifications

1. The candidate should be highly motivated and within three years of receiving a Ph.D. or M.D./Ph.D. degree.

2. The candidate should have a solid background and strong technical skills in biochemistry, molecular biology, cell biology, cancer biology, and mouse models.

3. The candidate should have a publication track record.

Application Instructions

Interested candidates should send a cover letter describing current and future research interests, a current CV with names and contact information for 2-3 references to Dr. Wenjian

Gan at wxg208@case.edu.

Equal Employment Opportunity Statement

Case Western Reserve University is an equal opportunity employer. All applicants are protected under federal and state laws and university policy from discrimination based on race, color, religion, sex, sexual orientation, gender identity or expression, national or ethnic origin, protected veteran status, disability, age and genetic information.

Reasonable Accommodation Statement:
Case Western Reserve University complies with the Americans with Disabilities Act regarding reasonable accommodations for applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity by phone at 216.368.3066 or by email at equity@case.edu. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.