Assistant Scientist

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The Diabetes Research Institute has an exciting opportunity for an Assistant Scientist, SOM position. The incumbent carries out a particular research agenda in support of the University’s research goals and objectives. Moreover, the Assistant Scientist, SOM contributes to the scientific community by publishing research findings and promotes the University’s reputation as a leader in the field.

CORE JOB FUNCTIONS                                                                                           

• Contributes to basic and applied research activities and authors scientific publications, technical and agency reports, and patent preparations.

• Collaborates with senior staff to publish findings in refereed journals.

• Creates and conducts experiments and analyzes results.

• Works with other researchers to use and develop end products.

• Writes extramural proposals with approval from appropriate senior staff.

• Provides ready access to all experimental data for managing staff.

• Requests or acquires equipment and supplies for assigned project(s).

• Uses the Internet, surveys, legal documents, and other available sources to collect information.

• Applies for grants to continue research and prepares materials for submission to granting agencies and foundations.

• Adheres to University and unit-level policies and procedures and safeguards University assets.

This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary.

CORE QUALIFICATIONS                                                                                        

• Ph.D., M.D. or other doctoral level degree relevant field

• Minimum 1 year of relevant experience

DEPARTMENT ADDENDUM

Department Specific Functions

• Serve as an expert using scientific flow cytometery knowledge and professional judgment in the design and implementation of FACS analysis for islet assessment and improvement methods.

• Responsible for on-call rotation in the GMP Facility for islet isolation, FACS analysis and other pancreas related activities

• Coordinate and conduct research activities related to improvement of islet isolation and maximization potency assay (beta cell fractional viability).

• Actively engaged in the operational and research and development (R&D) functions of the cGMP human cell processing division. Expected to have primary responsibilities for the isolation and processing of islet cells, iPSCs, Car T, and other somatic cell types that may be processed in conformance with strict FDA guidelines.  In addition to processing complex and technically demanding skills, the candidate must be able to exercise independent judgment and work without supervision through out the various stages of the cellular harvesting process (which may include isolation of cells through density gradient, separation, purification, or positive/negative selection using antibodies, determination of purity/quality, etc).  The cellular and products of these harvests are cultured, assessed, and prepare for infusion, shipment, translational research and/or clinical transplantation. The candidate is also expected to contribute actively to the development and testing of new methodologies and technologies, including the design and execution of experiments, the independent evaluation of new equipment, reagents, and other collateral materials, and to make recommendations based on expertise and experimental results. 

• Responsible for overseeing all equipment management activities for cGMP operations, including Installation Qualification (IQ), Operational Qualification (OQ), Performance Qualification (PQ), and equipment quality control, including preventive maintenance (PM).

RESPONSIBILITIES:

Responsible for troubleshooting the Flow Cytometers FACS analysis. The individual will also conduct cell analysis using various imaging equipment, perform data