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Director, Commercial / Marketing - US Neurology / Alexander Disease (AxD)

Ionis Pharmaceuticals
Remote, United States, United StatesRemotefull_timeVerifiedPosted 20 Dec 2025
💰 $220,000/yr($180,000/yr$220,000/yr)

About the role

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs.  With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees. 

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive. 

We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!

 

DIRECTOR, COMMERCIAL / MARKETING - US NEUROLOGY / ALEXANDER DISEASE (AxD)

 

SUMMARY: 

This pivotal commercial / marketing position represents an exciting opportunity to join a launch team in the US Commercial business (Neurology / AxD). Ionis’s long-term vision is to become a fully integrated biotech company, serving patients from rare- to broad-prevalence indications.

Zilganersen is poised to be Ionis’s first wholly owned neurology asset to launch in the US, setting the foundation for the future neurology pipeline.

The Commercial Director (Neurology / AxD) will be responsible for a broad scope of work and will be a key advisor to the Brand Lead / BU Head with responsibility and accountability for resolving critical commercial / brand issues and guiding strategic direction inclusive of market development, and leading HCP and Patient marketing and brand development. The successful candidate will play an integral role in the launch of zilganersen in AxD, collaborating closely with cross functional partners, to deliver on the success of zilganersen.

Reporting to the Brand Lead & Business Unit Head, Neurology / AxD, the ideal candidate will bring biotech/pharma commercial launch experience, a curiosity to uncover and experiment with innovation, a commitment to collaboration, and a drive to deliver a successful launch. This is a highly visible, high-growth role that requires strong strategic thinking, superior cross -functional collaboration, and the ability to operate at all levels of the organization. This is a unique opportunity to participate at the start of the build-out of the neurology commercial inline business that is positioned to have multiple launches in the coming years. Ionis is at the forefront of innovative science, defining and executing innovative and patient-centric solutions to deliver a transformational RNA Technology to patients with serious and fatal diseases. With an enterprise mindset, and long-term strategic thinking, this role will deliver impact to the broader organization by building the neurology franchise and future neurology pipeline readiness.

RESPONSIBILITIES:

  • Lead strategic Heath Care Provider (HCP) and Patient initiatives aimed to shape the AxD market, build a compelling brand, support a successful product launch, and drive brand growth
  • Responsible for executing market development through HCP and Patient / Caregiver DSE with AOR and omni teams
  • Create and deliver core brand elements, HCP and Patient campaigns, messaging, and core claims, ensuring alignment with strategy and complimentary to other key audience engagement plans
  • Develop field sales materials and patient facing materials with consistent pull-through of aligned messages
  • Partner closely with cross-functional partners and Above Brand Leads (Comm Ops, US MAx, Patient Services) to prioritize, focus, and gain alignment on the most impactful campaigns and associated messaging to deliver brand objectives
  • Lead opportunities for external influence with HCPs, including speaker bureau, congress strategy and execution, and expert t

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Company

Ionis Pharmaceuticals

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