Why Patients Need You

Our breakthroughs would not make it to the hands of patients without our pharmaceutical manufacturing team. We rely on a team of dedicated and agile members, who understand the importance and impact of their role in Pfizer’s mission. Patients need colleagues like you who take pride in their work and always look to improve outcomes. You will help to ensure that patients and physicians have the medicines they need, when they need them.

What You Will Achieve

We are seeking a highly motivated person as Manufacturing Engineer in our Drug Product Manufacturing (DPM) facility. The successful candidate will learn and actively support a wide range of process development and manufacturing activities for clinical drug product supplies. Additionally, the colleague will contribute to the development of DPM technology capabilities (eg. Powder blending, granulation, tablet compression, encapsulation, film coating etc.) by supporting novel process development and process understanding studies. The successful candidate must demonstrate strong teamwork dynamics when interfacing with various groups (e.g., Operations, Quality, Tech Support) and a continuous improvement mindset.

How You Will Achieve It

• Work as part of a multi-disciplinary team, liaising efficiently with Formulators, Engineers, Modelers, PAT scientists and Technicians, to deliver manufacturing campaign to produce solid dosage forms (tablets, capsules, multi-particulate etc.).
• Accountable for assisting technicians during the manufacturing campaigns using conventional or novel processes (e.g. Pfizer Continuous Manufacturing Module, powder blending, granulation, tablet compression, encapsulation, film coating etc.)
• Perform in-process operational checks associated with clinical manufacturing (examples include sample characteristic i.e. tablet friability and disintegration tests).
• Actively participate in completing and controlling GMP documentation such as (Batch Records, Logbooks, SOP’s etc.).
• Make contributions through troubleshooting processes, analyzing process data and provide technical insight to solve complex problems during manufacturing operations.
• Identify and aid the resolution of quality concerns; may assist with investigation reports in the quality system.
• Actively participate in and lead technical reviews on projects and contribute to the technical transfer processes to partner lines.
• Translate process data into useful information and present to partner lines during pre and post manufacturing including critical manufacturing information.
• Provide "hands-on" training for Manufacturing Technicians and contribute to department technical/GMP/safety training.
• Support the development of operational processes/systems and associated standard operation procedures.
• Assist with Equipment Lifecycle Management activities:
  • Participate in Site Acceptance testing, Qualification, Validation
  • Coordinate Plan Maintenance and Calibration activities for both facilities and equipment with associated division
  • Manage and maintain the inventory of the equipment change parts needed for daily operation.
• Assist continuous improvement initiatives throughout the manufacturing workstream and act as a change agent to incorporate improvements.
• Make recommendations for continuous improvement opportunities with regard to safety, quality, and efficiency.
• Support continuous improvement initiatives throughout the manufacturing workstream and act as a change agent to incorporate improvements.
• Utilize software tools (e.g. Pivision, Spotfire etc.) to create relevant key performance indicator dashboards and knowledge management practice.
• Ensure all operations are executed according to Pfizer and OSHA safety standards

Qualifications

Must-Have

• Bachelors Level qualification in Chemical Engineering, Pharmaceutical Sciences, Materials Science or other Engineering discipline. This role is suitable for a newly qualified graduate or graduate with some initial industrial experience.
• Effective verbal and written communication skills
• Strong stakeholder management skills and accountability in day-to-day interactions with an operational focus on business goals, customers and process required
• Demonstrated competency using Microsoft Word, Microsoft Excel, Microsoft Outlook, and additional software.

Nice-to-Have

• Suitable comprehension of engineering and manufacturing operations including processing, instruments, controls and mechanical aspects of pharmaceutical manufacturing equipment and associated services is preferred.
• Experience with data visualization software (i.e. Spotfire, Pivision, or Tableau) is preferred.