University of Colorado Anschutz Medical Campus 

Department: Barbara Davis Center for Diabetes – Basic Research Division

Job Working Title: Principal Staff Scientist

Position #:00841206 – Requisition #: 38054

Job Summary:

This role offers an exceptional opportunity to conduct high-impact research focused on uncovering the underlying causes of diabetes, with the goal of advancing treatment and prevention strategies. You will collaborate closely with leading scientists at the Barbara Davis Diabetes Center and the Department of Biochemistry and Molecular Biology, contributing to groundbreaking discoveries in diabetes research. The projects will explore pancreatic beta cell biology to uncover how beta cells contribute to autoimmune processes in type 1 diabetes and to functional impairment in type 2 diabetes. In particular, one line of investigation will examine how mRNA translation regulation shapes the production of neoantigens that drive autoimmune activation in type 1 diabetes. In this role, you will design, develop, and perform experiments using cellular systems, islets, animal models, and human samples to explore key molecular mechanisms—including mRNA translation, protein expression, beta-cell function, and immune cell infiltration.

Key Responsibilities:

·       Maintain islet and cell cultures

·       Maintain necessary animal cohorts

·       Design and perform experiments, primarily in molecular biology

·       Organize data and present to the group

·       Contribute to manuscript preparation for publication in peer-reviewed journals

Work Location:

Onsite – this role is expected to work onsite and is located in Aurora, Colorado.

Why Join Us:

The Barbara Davis Center (BDC) is a unique entity located on the University of Colorado Anschutz Medical Campus devoted to treating patients with Type 1 diabetes (T1D) and performing research to prevent and cure T1D. The BDC Research Division consists of 12 independent research labs focused on all aspects of T1D research including immunology, islet biology and stem cell biology. The Sussel lab uses sophisticated molecular techniques and mouse and human stem cell models to characterize the role of islet dysfunction in contributing to T1D.

Why work for the University?

We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:

• Medical: Multiple plan options
• Dental: Multiple plan options
• Additional Insurance: Disability, Life, Vision