Director, Preclinical Safety

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn. 

Job Description

As part of the Investigational Toxicology and Pathology team, the Director, Preclinical Safety will assess the safety of experimental compounds in animals as well as through use of in vitro systems. Data generated serves to enable project teams to de-risk and advance candidate compounds through early stages of development. The pathologist also acts as subject-matter expert and scientific resource for other departments, working cross-functionally as a key contributing member to project teams. Additional tasks include design and conduct of study protocols, evaluation of clinical and anatomic pathology data, presentation of data, and preparation of reports. The successful candidate will be scientifically curious, a team player, and strive to deliver innovative solutions to improve patients’ lives.

Responsibilities

• In cooperation with the toxicology department the pathologist designs, directs, conducts, and evaluates studies to determine the potential toxicity of experimental compounds in different species of animals. This involves interpretation of data in the field of pathology (necropsy, histopathology, clinical pathology, electron microscopy, etc.)
• Integrates the anatomic pathology data, clinical pathology data, and other study findings to generate a pathology report as a component of the toxicology report.
• Provides input to study protocols, supervise necropsies, perform histological examinations in rodent and non-rodent studies, author pathology reports, conduct peer reviews, and review regulatory documents.
• Partners with regulatory toxicologists, pathologists, pharmacokineticists, pharmacologists, and other functions to develop optimal strategies to address specific toxicology issues as well as select and advan