Lead Technical Program Manager, AI Development

Hybrid: Persons in these roles are expected to spend part of their time on-site in our Seattle offices and may occasionally work remotely from their home in the Greater Seattle area. On-site requirements vary based on position and team. If you have questions about Hybrid work arrangements for this role, please ask your recruiter.

Compensation: Our base salary range is $159,840 - $239,760, and in addition we have generous bonus plans to provide a competitive compensation package. 

Who You Are:

You are a seasoned technical program manager who is passionate about the potential of AI to solve real problems impacting humanity, such as how we understand and treat cancer. You thrive in greenfield environments, adapt quickly to evolving challenges, and are comfortable wearing multiple hats. With a strong track record of taking on increasing leadership responsibilities, you are prepared to play a pivotal role in driving critical AI initiatives forward.

You excel at building and maintaining strategic relationships, understanding partner priorities, and fostering collaboration to create mutual value. A skilled communicator, you can translate complex technical concepts into compelling narratives for diverse audiences, ensuring alignment and engagement across stakeholders.

Who We Are: 

You’ll be joining the program management team within our Strategic Infrastructure (SI) group, responsible for driving the definition and execution of AI2’s ambitious flagship projects, including "truly open" foundation models, AI agents for science, and AI-for-environment initiatives. Our centralized team works directly with world-class researchers to connect the dots between R&D, engineering, and real-world impact. We are deeply involved in technical details while also serving as stewards of the institute's big-picture strategy. Our work spans all levels of the organization—from coordinating with the team operating our state-of-the-art GPU cluster to collaborating directly with executives to drive clarity, decision-making, and prioritization.

Your Next Challenge:

AI2 has recently expanded our R&D portfolio and joined the Cancer AI Alliance (CAIA) spearheaded by the Fred Hutch Cancer Center, with the goal of building the world’s most comprehensive laboratory for creating and deploying cancer AI models. You’ll be responsible for leading AI2’s engagement with CAIA, ensuring seamless collaboration across cancer centers and technology partners. Additionally, you will serve as the TPM lead for R&D workstreams focused on privacy-preserving AI, a critical component of CAIA’s success.

The essential functions include, but are not limited to the following:

• Represent AI2 in coordination meetings with other alliance members, fostering relationships that enhance collaboration and innovation.
• Apply an understanding of the broader context surrounding initiatives to identify external risks and opportunities; productively drive strategic changes when necessary.
• Define and implement program management systems, answering key questions about how best to structure working teams, how to make the right decisions efficiently, and how to communicate across the team for strong collaboration and alignment.
• Ensure transparent communication with leadership and other stakeholders, including progress updates, risks, and mitigation strategies.
• Demonstrate leadership within the PM organization by modeling a growth mindset, identifying opportunities for process improvement, and fostering a high-performance culture.

What You’ll Need:

• 12+ years of experience in product or program management
• BS degree in Computer Science, Data Science, Statistics, Engineering, Applied Mathematics, or equivalent professional experience
• Experience building a successful major product or experience in collaboration with external partners.
• Experience in AI, specifically large-scale neural networks.
• Experience working in a research environment.
• Excellent communication skills, both written and verbal; deft at adapting communication style to fit different audiences (technical, non-technical, executive level).

Bonus qualifications

• Experience as a people manager
• Experience in healthcare and/or biomedical domain
• Experience in applications with highly sensitive data

Physical Demands and Work Environment:

The physical demands described here are representative of those that must be met by a team member to successfully perform the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the functions.

• Must be able to remain in a stationary posi