Senior MES Engineer

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Position Summary:

The Senior MES Engineer is a strong technical subject matter expert (SME) responsible for the design, implementation, and support of Manufacturing Execution System (MES) solutions within the Devens Cell Therapy Facility. Leveraging deep expertise in Emerson Syncade MES and manufacturing systems, this role resolves complex challenges, enforces governance procedures, and drives the delivery of innovative digital solutions. The Senior MES Engineer collaborates across functions and the broader network to ensure operational consistency, regulatory compliance, and continuous improvement, while influencing the technical direction of MES initiatives.

Duties/Responsibilities:

MES Business Analysis & Recipe Authoring:

• Analyze MES requirements and implement recipe modifications to meet evolving business needs.

• Ensure recipes align with operational objectives, regulatory standards, and best practices.

Business Process Expertise:

• Develop an in-depth understanding of assigned manufacturing processes.

• Support investigations and identify opportunities for recipe optimization and process efficiency.

Governance & Standards:

• Establish, document, and maintain MES recipe authoring standards, guidelines, and templates.

• Ensure consistency, compliance, and efficiency across all recipe development activities.

Training & Knowledge Transfer:

• Create and deliver training materials to onboard and upskill MES authors, engineers, and end-users.

• Foster knowledge sharing and best practices adoption across teams.

Operational Support:

• Provide rotational on-call support for MES-related issues during off-hours.

• Partner with manufacturing operations to resolve incidents, minimize downtime, and ensure uninterrupted production.

Reporting Relationship:

• The Senior MES Engineer reports into the IT Digital Plant organization. The role contributes to the design, testing, documentation, and deployment of MES solutions, while adhering to governance procedures and supporting IT projects of moderate to high complexity.

• This position serves as a technical subject matter expert—supporting operations, troubleshooting issues, ensuring regulatory compliance, and driving the adoption of digital solutions that enhance manufacturing performance.

Qualifications:

Education:

• Bachelor’s degree in Engineering, Computer Science, or related discipline.

Experience:

• 3–5 years of experience as an MES Engineer (or equivalent role) within the Biologics, Pharmaceutical, or Cell/Gene Therapy industries.

• Strong expertise in Emerson Syncade MES, including recipe authoring and troubleshooting.

• Proven ability to understand manufacturing processes and translate business needs into MES solutions.

Skills:

• Excellent analytical and problem-solving skills, with the ability to propose effective, data-driven solutions.

• Strong interpersonal and communication skills; effective at collaborating across functions and influencing stakeholders.

• Experience developing and delivering technical training is strongly preferred.

• Familiarity with recipe authoring tools, data integrity principles (21 CFR Part 11, Annex 11), and cGMP standards.

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