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Distinguished Scientist – Transgenic Model & Technology
SanofiMontpellier, Francefull_timeVerifiedPosted 28 Jul 2026
💰 €101,333/yr(€76,000/yr – €101,333/yr)
About the role
Senior Distinguished Scientist – Transgenic Model & Technology - CDI
- Location: Montpellier / Vitry-sur-Seine, France
- Candidates must be willing to travel internationally as part of this position
About the job
As Senior Distinguished Scientist within our Translational In Vivo Models (TIM) team, you'll lead our global Transgenic Model & Technology function and drive innovation in genome engineering to accelerate drug discovery across all therapeutic divisions. Ready to get started?
Join the engine of Sanofi's mission where deep immunoscience meets bold, AI-powered research. In R&D, you'll drive breakthroughs that could turn the impossible into possible for millions.
About Sanofi:
The Translational In Vivo Models (TIM) department within Sanofi's R&D is seeking an exceptional Senior Distinguished Scientist to lead our Transgenic Model & Technology (TMT) function globally. This strategic leadership role will drive innovation in genome engineering and genetically modified model development to accelerate drug discovery across all therapeutic divisions.
As the global head of Transgenic Biology, you will ensure our organization remains at the forefront of technical developments in genome engineering, enabling breakthrough discoveries in immunology, immuno-inflammation, rare diseases, neuroscience, and oncology. You will serve as a key scientific advisor and strategic thinker, shaping the direction of in vivo and preclinical research programs while championing the integration of emerging technologies, including AI and digital platforms — into transgenic science.
Main responsibilities
- Lead and advance state-of-the-art genome engineering and CRISPR-based strategies for in vivo model development, covering immunology, rare diseases, neuroscience, and oncology.
- Identify, evaluate, and implement new technologies and innovations in transgenesis, CRISPR/Cas systems, and emerging genome engineering platforms.
- Champion AI and digital integration to enhance model design, data analysis, and predictive capabilities in transgenic research.
- Serve as strategic scientific advisor to research projects across therapeutic areas, providing expert guidance on in vivo and preclinical study design.
- Align transgenic capabilities with organizational research priorities and long-term scientific goals through strategic planning and cross-functional leadership.
- Lead transversal teams and projects across multiple therapeutic divisions, sites, and external partners, collaborating with program leaders, cluster heads, and department heads.
- Drive budget planning, forecasting, and financial management to optimize resource allocation and operational efficiency.
- Build and manage strategic partnerships with model providers, CROs, and academic partners, including negotiation of license agreements and contracts.
- Supervise, mentor, and develop a high-performing team, fostering a culture of scientific excellence, innovation, and continuous learning.
What we offer you:
A fixed salary over 12 months, supplemented by a short-term incentive, as well as a collective variable compensation based on Sanofi Group results.
Because taking care of our employees is also our mission: 31 days of paid leave + RTT depending on your status, remote work up to 2 days/week, quality health insurance, public transport coverage up to 80%, extended maternity/parental leave (18/14 weeks), Group Savings Plan & PERCOL with employer matching, PERO, numerous CSE benefits, internal and international mobility opportunities, learning & development opportunities, and many other benefits to discover here.
About you
Experience:
- Extensive post-doctoral or industry experience in mouse molecular genetics and transgenic animal model development
- Demonstrated track record of scientific leadership in an academic or pharmaceutical/biotech research environment
Technical skills:
- Deep expertise in developing transgenic animal models, including engineering diverse genetic alleles using CRISPR/Cas9, Cas12, base editors, prime editors, and other advanced genome engineering systems
- Comprehensive knowledge of both theoretical principles and
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