Director of Cyber Threat Intelligence (CTI)

About AstraZeneca 

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company dedicated to discovering, developing, and commercialising prescription medicines for serious disease. We’re committed to being a Great Place to Work. 

About the Role 

The Director of Cyber Threat Intelligence will lead a highly technical CTI function within AstraZeneca’s Cybersecurity Operations division, managing a team of analysts to deliver strategic, operational, and tactical intelligence that measurably reduces risk across the enterprise, including manufacturing, clinical trial platforms, and R&D environments. This role anchors CTI to “intel-to-action” outcomes, partnering closely with Vulnerability Management, Detection Engineering, and Incident Response to harden controls, prioritize patching, improve detections, and accelerate response. 

Key Responsibilities 

• Program Leadership and Strategy: Define CTI vision, operating model, and roadmap aligned to AstraZeneca’s cyber risk reduction strategy, with special emphasis on manufacturing continuity, clinical data integrity, and R&D IP protection. 

• Adversary Prioritization Framework: Design and operate a scoring rubric that ranks actors based on intent/capability/relevance, TTP emergence and prevalence, organization-specific exposure to known vulnerabilities/CVEs, and global “viral” events, maintaining dynamic watchlists and escalation triggers. 

• MTTI Metric and Analytics: Implement analytic methods to estimate mean time-to-impact per adversary (from initial access to material business impact) using internal telemetry, historical incidents, industry reporting, and confidence levels, performing comparisons with IR’s MTTC to drive control improvements. 

• Attack Path Modeling: Build and maintain end-to-end attack path models from initial access to material impact across IT-to-OT pivots, clinical platforms, and R&D environments, mapping steps to MITRE ATT&CK (Enterprise/ICS), identify control gaps and choke points, derive detections-as-code and hunt hypotheses, and support validation efforts including purple-team exercises and adversary emulation to ensure enterprise hardening and measurable risk reduction. 

• Dark Web and Closed-Source Monitoring: Establish collection and monitoring across dark web forums, marketplaces, breach dumps, and closed channels to identify emerging TTPs, credential leaks, data exposure, access-broker listings, and targeting of manufacturing, clinical, or R&D assets, integrating validated findings into TIP/SIEM pipelines, trigger takedown requests where feasible, and deliver rapid advisories with confidence ratings and specific actions for Vulnerability Management, Detection Engineering, and IR. 

• Third-Party and Ecosystem Intelligence: Deliver risk insights for CROs/CMOs/logistics/technology vendors, monitor credential leakage and domain spoofing, and support/coordinate takedown operations when needed. 

• Structured Threat Actor Attribution (Diamond Model): Lead disciplined attribution using the Diamond Model (adversary, capability, infrastructure, victim) and complementary frameworks, correlating TTPs, tooling lineage, code-reuse, infrastructure overlaps, and victimology with c