Director, Supply Chain Planning

Company Overview:

Dyne Therapeutics is discovering and advancing innovative life-transforming therapeutics for people living with genetically driven neuromuscular diseases. Leveraging the modularity of its FORCE™ platform, Dyne is developing targeted therapeutics that deliver to muscle and the central nervous system (CNS). Dyne has a broad pipeline for neuromuscular diseases, including clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD) and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. For more information, please visit https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook. 

Role Summary:

The Director of Supply Chain Planning is responsible for end-to-end inventory and production planning across Dyne’s external supply network. This includes long-range planning (LRP), ensuring uninterrupted clinical supply, and supporting commercial launch readiness through scenario-based planning and risk assessments. This strategic role is critical in executing current planning activities and shaping future supply chain capabilities. The Director collaborates cross-functionally with Process Development, Research, CMC, Quality, Clinical Operations, and Commercial teams. It is an opportunity to help shape the future of Dyne’s supply chain function during a critical period of growth and innovation.

This role is based in Waltham, MA without the possibility of being fully remote.

Primary Responsibilities Include:

• Collaborate with cross-functional partners in CMC, Logistics, Quality, Clinical Operations, and Commercial to develop and maintain a reliable demand and supply plan, ensure uninterrupted product availability for patients, support commercial readiness, and align with the company’s business objectives.
• Maintain an understanding of external manufacturing site capacities, capabilities, and supply risks.
• Identify and implement opportunities to optimize supply chain processes and drive efficiencies.
• Lead scenario planning to evaluate alternative demand and supply assumptions and inform risk mitigation strategies.
• Lead monthly demand and supply planning meetings with cross functional team members as part of our drive to a formal Integrated Business Planning / Sales and Operations Planning process.
• Perform analysis of Dyne portfolio, including inventory projections, supply performance and risks.
• Integrate with other global planning processes to monitor key performance indicators (KPIs) and analyze supply chain data to identify opportunities for improvement and cost savings.
• Author Supply Chain-related standard operating procedures (SOPs) and work instructions.
• Manage relationships with third-party suppliers and vendors to ensure timely delivery of materials and components.
• Ensure compliance with regulatory requirements and quality standards in supply chain operations.

Education and Skills Requirements:

• Bachelor’s degree in Supply Chain, Business, Engineering, or a related field; advanced degree preferred. Minimum of 10 years of relevant experience in a biotech, pharmaceutical, or life sciences environment.
• Ability to effectively plan, prioritize, execute, follow up and anticipate challenges.
• Experience managing complex schedules and priorities in dynamic pharmaceutical, biotech or related environments.
• Ability to work, influence, and gain agreement across multiple functions.
• Strong analytical, problem solving and critical thinking skills.
• Strong knowledge of supply chain best practices, inventory management, and demand forecasting.
• Proficiency in advanced Excel functions and familiarity with planning and analytics tools such as Smartsheet, Visio, ERP systems (e.g., SAP, Oracle), and Power BI.
• Collaborative work style to be part of a team to identify process gaps and develop solutions.
• Excellent interpersonal, verbal, and written communication skills.
• Experience in supply chain, drug development, project management, and/or pharmaceutical manufacturing/packaging.
• In-depth working knowledge of regulations relating to clinical manufacturing, packaging and distribution activities (CGMP, GCP).
• APICS or CSCMP certification a plus.

 

 

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The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibi