Executive Director, Real World Evidence

Band

Level 7

 

Job Description Summary

Location: Remote: This position can be based remotely in US. Please note that this role would not provide relocation as a result. The expectation of working hours and travel (domestic and/or international) will be defined by the hiring manager.

 

Job Description

The Executive Director, Head of Real-World Evidence (RWE) is a senior leadership role within the US Evidence Generation team, providing strategic vision and leadership for RWE activities across the company’s entire therapeutic portfolio. Reporting to the Vice President of Evidence Generation, this position oversees a multidisciplinary team to: 

• Shape and execute RWE data strategies in US Medical Affairs, leveraging innovative data sources to drive impactful research. 

• Implement measurement strategies for clinical care gap assessments. 

• Deliver regulatory-grade, high-quality observational research that informs clinical, regulatory, market access, and commercial decision-making across all stages of the product lifecycle. 

 

This role requires a highly experienced thought leader with both technical expertise and strategic vision to advance innovative, scientifically robust evidence for priority assets. The successful candidate will guide the evaluation and application of observational research methods and analytical techniques, while leading and mentoring a team of RWE professionals in the US and across the NOCCs. 

Key Responsibilities:

• Develop and execute comprehensive US-focused RWE strategies aligned with company business priorities across all therapeutic areas. 

• Provide strategic oversight for evidence generation plans for the complete product portfolio within the US market. 

• Collaborate with the VP of evidence generation and medical affairs leadership to integrate RWE insights into strategic decision-making. 

• Ensure alignment of US RWE strategies with global evidence generation initiatives. 

• Lead and inspire a cross-portfolio team of RWE directors, managers, and specialists covering multiple therapeutic areas. 

• Provide mentorship, career development, and performance management for direct reports. 

• Foster a culture of scientific excellence, innovation, and collaboration within a matrix organization. 

• Manage team resources, budgets, and strategic priorities for US-focused RWE initiatives. 

Minimum Requirements:

Work Experience:

• 10+ years of relevant work experience with a focus on evidence generation, specifically a focus on real-world evidence methodologies / approaches (strongly preferred). 

• Proven track record of successful leadership, with demonstrated ability to influence work and align with multiple internal and external stakeholders. 

• Strong knowledge of HCP and Payer evidence needs and what is required to support these needs. 

• Previous leadership responsibility with demonstrated ability to think and act strategically and proven tactical experience and delivery of results. 

• Strategic mindset with the ability to anticipate challenges, identify opportunities, and develop innovative solutions to achieve regulatory objectives. 

• Strong leadership skills with the ability to effectively lead and motivate a multidisciplinary team, foster collaboration, and drive results in a fast-paced and dynamic environment. 

• Ability to conduct and oversee clinical data analysis, epidemiology, and biostatistical elements of RWE and epidemiology. 

• Pro