Director, Translational Medicine

This is what you will do:

The Director of Translational Research will be responsible for:

Translational activities for rare nephrology focused translational research group within the Translational and biomarker research group at Alexion, AZ rare disease Research Department in New Haven.   Setting and overseeing the implementation of translational and biomarker objectives for nephrology assets. Ensuring seamless collaborations between research and development and to drive establishment of strong target to disease linkage to support data driven decision making. Leading a cross functional team  for a) the identification of new indications for Alexion therapeutics; b) the functional differentiation of Alexion targets from competitors; c) driving rigorous translational understanding of clinical trial data, d) drive key translational/BM hypothesis for treatment response or non-responsiveness e) lead efforts to drive translational research strategy for the different programs in nephrology TA

You will be responsible for:

• Leading a group of scientists with diverse scientific and technical background.
• Represent translational research in programs at target selection stage onwards to drive strong translational data packages.
• Lead by example and drive scientific rigor and innovation, integrate latest cutting-edge technological advancements to deliver on translational research packages.
• Collaborate with research leaders to provide strategic oversight for
• portfolio and people.
• Effective networking within the research & development organization and governance structures to understand the portfolio and be able to anticipate and proactively address translational gaps.
• Use scientific and leadership expertise to drive strong performance of group by recruiting, retaining and developing scientists.
• Actively participate in Alexion’s internal scientific and strategic meetings, scientific advisory board meetings and experts’ conferences by presenting and critically evaluating the science and contributing to the evaluation of projects

You will need to have:

• Ph.D. in the biological sciences
• At least 10 years of relevant translational and biomarker experience and at least 10 years of leadership experiences experience in the biotechnology or pharmaceutical industry
• Strong knowledge of the pathogenesis of rare diseases especially in nephrology indications and the application of cellular, molecular technologies and models to drive program decisions, including those related to supporting value propositions, Research Target Profiles and biomarker discovery.
• Strong leadership abilities for project teams and line management responsibilities, and an ability to bring together diverse skill sets to form a cohesive team.  Strong written and oral communication skills, including cross-functional collaborative and communication skills
• Ability to prepare technical reports, publications and oral presentations

We would prefer for you to have:

• Prior experience working within translational research organization.
• Prior experience in BM efforts and IND filing
• Establishing and leading external partnerships in rare nephrology indications

Date Posted

23-May-2024

Closing Date

25-Aug-2024Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact accommodations@Alexion.com. Alexion participates in E-Verify.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.