Sr/Principal Scientist, Computational Biology

FL87, Inc. is a privately held, early-stage biotechnology company developing a novel approach to gene therapy that can address currently untreatable diseases.

FL87 was founded by Flagship Pioneering, an innovation enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Syros Pharmaceuticals (SYRS), Seres Therapeutics (NASDAQ:MCRB), Generate Biomedicines, Tessera Tx, Evelo Biosciences (EVLO), and Indigo Agriculture.

Position Summary:

We are searching for an experienced Senior/Principal Scientist to drive computational innovation in a well-funded biotech pioneering novel nucleic acid therapeutics. We are looking for an individual who is excited to innovate a new class of programmable medicines. This individual is expected to bring excellent scientific rigor and creativity, and a track record of using diverse computational methods to create value. This individual will have the opportunity to work in a dynamic and fast-paced entrepreneurial environment as part of a highly collaborative and rapidly growing team.

Key Responsibilities:

• Play a leading role in advancing platform development by using computational methods to drive innovation
• Develop and perform bioinformatics analyses, such as on bulk and single-cell DNA/RNA sequencing data, or publicly available databases for sequences and biological insights of interest
• Analyze, troubleshoot, and communicate findings clearly and succinctly in oral, written, and visual formats
• Prepare written and visual materials for internal and external audiences

Work independently and collaboratively in a multidisciplinary team environment

Qualifications:

• PhD in relevant discipline (Genomics, Computational Biology, etc.) with >3 years of industry experience
• Extensive working experience with analyzing data from diverse sequencing platforms, including Illumina (bulk and single-cell), Oxford Nanopore MinION, and Sanger -
• Extensive working experience with relevant programming languages, including Linux, R, and Python
• Extensive working experience with AWS infrastructure and pipeline development methods (Docker, Snakemake, etc.)
• Strong communication, team leadership, and interpersonal skills.
• Track record of working effectively in a multidisciplinary environment, interacting with teams from other line functions
• Strong organizational, analytical, problem-solving, and project management skills.
• Ability to thrive in a fast-paced, multidisciplinary, and rapidly growing biotech