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Principal Software Engineer, Research Systems

Gilead Sciences
Foster City, United Statesfull_timeVerifiedPosted 8 Apr 2026
💰 $219,120/yr($169,320/yr$219,120/yr)

About the role

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
 

Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact.
 

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.

Job Description
 

Gilead's mission is to discover, develop, and deliver therapies that will improve the lives of patients with life-threatening illnesses worldwide. The Principal Software Engineer – Research Systems is a senior individual contributor and domain expert responsible for end-to-end support, configuration, and evolution of Dotmatics project pages and associated research workflows. This role is less focused on enterprise architecture ownership and more on deep partnership with scientists, operational excellence, and service-oriented delivery of high-quality research system experiences.

The individual operates with a high degree of autonomy, serving as a trusted point of contact for scientific users, owning the creation and maintenance of Dotmatics project pages, ensuring data is fit-for-purpose, and providing clear communication on system status, changes, and support requests.

Key Responsibilities:

  • Recognized as a subject matter expert for Dotmatics project pages and associated research workflows.

  • Operates independently with minimal direction, owning outcomes for user satisfaction and system effectiveness.

  • Impact is measured by quality of scientific enablement, user adoption, system reliability, and service responsiveness.

  • Serves as a bridge between scientists, IT, and platform teams, ensuring research systems evolve in a controlled, user-centered manner.

Dotmatics Project Page Ownership

  • Own the design, creation, configuration, and ongoing maintenance of Dotmatics project pages in close collaboration with scientists and research stakeholders.

  • Work directly with scientific users to identify appropriate data, metadata, and structures required to support project goals, ensuring usability, consistency, and scientific relevance.

  • Translate scientific workflows and requirements into well-structured Dotmatics project pages that support data capture, analysis, and decision-making.

  • Continuously improve existing project pages based on user feedback, evolving scientific needs, and platform capabilities.

Scientific Partnership & Customer Service

  • Act as a primary point of contact for scientific users, providing responsive, high-quality customer service in support of Dotmatics and related research systems.

  • Respond to email enquiries from users, including troubleshooting issues, answering questions, and providing guidance on best practices.

  • Proactively communicate system status, planned changes, incidents, and resolutions to users in a clear, professional, and timely manner.

  • Build strong working relationships with scientists, informatics partners, and operational teams based on trust, reliability, and domain expertise.

Training & Enablement

  • Develop and deliver training for bespoke logistics and research systems, including Dotmatics-related workflows and integrations.

  • Create and maintain training materials such as user guides, walkthroughs, and onboarding documentation.

  • Provide hands-on support during onboarding of new users, projects, or capabilities, ensuring successful adoption of systems.

IT Collaboration & Platform Evolution

  • Liaise closely with IT and platform teams on Dotmatics implementation, configuration, upgrades, and validation activities.

  • Support implementation and upgrade projects, including user acceptance testing, regression testi

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Company

Gilead Sciences

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