Sr. Manager, Commercial CAR-T Operations

Company Information

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell and natural killer (NK) cell-based immunotherapy. 

Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel) in 2017. Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.

Legend Biotech is seeking Sr. Manager, Commercial CAR-T Operations as part of the Commercial team. 

Role Overview

Under the direction of the Executive Director of Commercial & CAR-T Operations, the Sr. Manager, Commercial CAR T Operations is responsible for supporting all aspects of U.S. CAR-T operations. This includes activities such as execution and implementation of strategic CAR T Operations plans, professional onboarding and qualification/certification of sites, collaboration with internal and external CAR-T stakeholders, including participation in Legend/Janssen alliance activities, cross functional project team leadership, and external partner / client program support.

Key Responsibilities  

• Build and maintain close relationships with key internal stakeholders and functions in the areas of marketing, sales leadership, supply chain, manufacturing, clinical, and medical.
• Develop operational capabilities for external CAR-T operators for both clinical and commercial CAR T institutions in the U.S.
• Contribute to the enhancement of the CAR T Commercial Operations platform
• Manage and support CAR T operations and account/site onboarding to ensure CAR T institutions certification
• Design customer experience and site operations programs within functional areas
• Develop operational capabilities to evaluate and assess, in real time, CAR T center capacity, capabilities and infrastructure, ensuring the implementation of relevant processes and SOPs, and ensuring proper preparation (training, logistics, RMP, etc.) of all dedicated internal and external functions
• Evaluates customer and operational needs to develop and improve performance metrics
• Develop & implement commercial order support program analysis and reporting capability
• Defines data and analytics strategies, and ensured platform validation and deployment strategies are in place to turn models and solutions into deliverables and actionable insights
• Anticipates and incorporates emerging influential trends and customer feedback into future design concepts
• Coaches others to support data governance and data management guidelines

Requirements

• University degree (B.A. /B.S.) required, life science, informatics, and/or healthcare management preferred. Master’s degree a plus.
• 10+ years Pharma / Biotech experience, or equivalent in Life Sciences Consulting.
• Hematology/oncology knowledge, experience in the field of allogeneic transplantation and/or cellular therapies (CAR T), preferred
• Experience with Machine Learning, Artificial Intelligence, or other programming languages is highly desired.
• Experience in customer centric operations, with preference to direct experience interacting with Oncology Centers of Excellence
• Experience working with remote field based employees
• Proven track record in working across relevant stakeholders(s), e.g. medical, sales, marketing and/or account management
• Strong project and process management skills, IT technical competencies, prior experience with cell therapy Chain of Custody / Chain of Identity IT solutions preferred (i.e. Vineti)
• Strategic and analytical thinker, with a well-balanced medical/science, technical and commercial mindset
• Strong communication and negotiation skills (verbal/written), ability to build and maintain reliable internal customer relationships
• Skilled team player, with collaborative mindset and proven experience in team coordination and/or cross-functional leadership
• Extensive knowledge of U.S. healthcare environment, applicable laws, regulations and standards preferred
• Agile learner with the ability to work effectively in complex, rapidly changing environments and to prioritize activities effectively
• Strong analytical capabilities with emphasis on data collection and analysis methodologies.
• Advanced skills in PowerPoint, Excel, and Access.