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Scientist High-Throughput Purification

Bristol Myers Squibb
United Statesfull_timeVerifiedPosted 3 Aug 2024

About the role

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

BMS encompasses a broad range of disciplines to enable a robust pipeline of drug candidates aimed at serious diseases.  Chemistry is a core capability in Small Molecule & Drug Discovery with innovative scientists working in medicinal chemistry, radiochemistry, analytical chemistry, and large-scale synthesis.  Within SMDD our Lead Discovery and Optimization (LDO) team is responsible for high throughput screening, compound storage and distribution, primary assays to support discovery programs, and compound profiling to explore drug liabilities in vitro.   LDO scientists discover and adopt cutting edge assay technologies that utilize state-of-the-art automation to drive speed and efficiency.  Our Molecular Structure and Design team embraces novel approaches to computer-aided drug design, machine learning, and structural biology.  The integration of these disciplines provides a seamless and highly interactive environment for discovery scientists to learn, develop, and innovate.  Working in partnership with our disease area experts in the Thematic Research Centers provides an exciting pathway to discover and deliver medicines to patients in need.

This individual will be responsible for providing automation and technology support for a team engaged in non-GLP, high-throughput purification at Bristol Myers Squibb in Lawrenceville, NJ.  He or she will be a member of the team focused on centralized, high-throughput purification utilizing reverse phase and supercritical fluid chromatography that relies on close coordination of scientists, instruments, automation, and bespoke software.  Through the identification and successful implementation of continuous improvement projects including infrastructure improvements, IT and process improvements, obsolescence de-risking, and quality improvements, the individual will be expected to influence the tactical plans and strategies for separation science at multiple research sites within BMS.  He or she will also ensure operational support of a fleet of liquid handlers, robotics, and analytical and preparative LCMS and SFCMS instruments used by the purification team across multiple geographies.  The candidate will work with other team members and a group of on-site functional service providers to ensure that the infrastructure is fully operational.  The candidate will also interface with IT teams, OEM engineers and technicians, and fabrication specialists to accomplish lab and instrument enhancements and trouble shoot and remedy challenges in the lab environment.

Expected competencies include:

  • Strong written and oral communication skills
  • The successful candidate must be able to work independently and matrix across teams.
  • Must have a proven record of accomplishment in successful project execution.
  • The candidate will have demonstrated problem-solving skills, including troubleshooting workflows and processes, instruments, and data management issues. 
  • Experience in automation, particularly lab automation, computer programming (one or more common or instrument-specific languages), data visualization, and/or process optimization are highly desired.

Basic qualifications:

Bachelor's Degree with 5+ years of academic/industry experience

Or

Master's Degree with 3+ years of academic/industry experience

Or

PhD in Chemistry and no years of experience

Preferred qualifications:

  • Master's Degree with 3+ years of academic/industry experience or PhD with no experience required.
  • Experience in a high throughput environment managing large numbers of samples and associated data.
  • Experience in analysis and purification of small molecules and/or peptides by reverse phase HPLC an

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Company

Bristol Myers Squibb

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