SR. RESEARCH ASSOCIATE/ASSOCIATE SCIENTIST, NONCLINICAL DEVELOPMENT
Adicet BioAbout the role
<div class="content-intro"><p><strong>JOIN US!</strong></p> <p>Adicet Bio, Inc. is a clinical stage biotechnology company discovering and developing allogeneic gamma delta T cell therapies for autoimmune diseases and cancer. Adicet is advancing a pipeline of “off-the-shelf” gamma delta T cells, engineered with chimeric antigen receptors (CARs), to facilitate durable activity in patients. For more information, please visit our website at <a href="https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fwww.adicetbio.com&esheet=54175567&newsitemid=20250108585728&lan=en-US&anchor=https%3A%2F%2Fwww.adicetbio.com&index=1&md5=9d942dbcdb299f0c9fe719a48148cd0e">https://www.adicetbio.com</a>.</p></div><p><strong> RESEARCH ASSOCIATE/ ASSOCIATE SCIENTIST, NONCLINICAL DEVELOPMENT</strong></p> <p><strong> </strong></p> <h4><strong>Key responsibilities: </strong></h4> <ul> <li>Coordinate and execute in vivo and ex vivo nonclinical studies to evaluate Adicet’s immune-cell and gene-therapy platforms, including efficacy, pharmacokinetic/pharmacodynamic, and safety assessments in relevant murine oncology and immunology models.</li> <li>Contribute to study design, experimental planning, timeline development, and data-driven decision-making to support program advancement.</li> <li>Collaborate and communicate effectively with cross-functional teams and external contract research organizations to coordinate study execution, troubleshoot technical challenges, and ensure study endpoints align with program objectives</li> <li>Perform necropsies and process tissues for downstream analyses, including flow cytometry, qPCR/ddPCR, and ELISA, to characterize pharmacologic activity and elucidate mechanisms of action.</li> <li>Maintain accurate, complete, and well-organized experimental records in accordance with internal documentation and quality standards.</li> </ul> <h4><strong>Qualifications:</strong></h4> <ul> <li>Bachelor’s degree in biological sciences or a related field with 5+ years of relevant R&D experience, or a Master’s degree with 3+ years of experience, preferably in immuno-oncology, within an industry setting.</li> <li>Significant experience designing, executing, analyzing, and interpreting in vivo studies using murine xenograft disease models and/or humanized immunology models.</li> <li>Demonstrated proficiency administering therapeutic agents and establishing xenograft models through intravenous, intraperitoneal, and subcutaneous routes in mice.</li> <li>Strong technical proficiency in blood collection, including submandibular and tail-vein sampling, as well as tissue necropsy and
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