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Position: Senior Principal Scientist

Location: New Brunswick, New Jersey; Summit, New Jersey

Business Unit Overview
Our Drug Product Development team is committed to CMC design, development, and commercialization of innovative drug products to improve patient lives. We leverage the best people, collaboration, and cutting-edge innovation to achieve this commitment. BMS’s internal engine of innovation includes unrivaled industry leading expertise in CMC development of small molecules, protein biotherapeutics, protein degraders, and other therapeutic modalities. We collaborate closely with our colleagues in R&D and Commercial to design our drug products. Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope.

Position Summary
Bristol Myers Squibb is seeking a senior principal scientist to join the Oral Product Development group within the Drug Product Development function. The drug product development group supports the formulation and process development of Bristol Myers Squibb’s drug candidates from preclinical stage to commercial process readiness.  This position is responsible for formulation design, development, characterization, and technology transfer to enable development of small molecule drug products (DPs). The incumbent will be accountable to develop oral formulations and / or serve as a matrix team leader to lead formulation development as well as providing necessary guidance and support of drug product control strategy for drug candidates across all stages of development.

Key Responsibilities
The Senior Principal Scientist will collaborate across BMS sites with Drug Product, Analytical, API, Quality, and Regulatory functions to execute drug product formulation/process development, formulation strategies, control strategies, and support of drug application submissions and approval.

• Key member of a dynamic scientifically driven team, dedicated to the design, development, and characterization of robust small molecule drug product formulations.
• Develops oral formulations for clinical studies and commercialization.
• Leads drug product formulation and process development including evaluating the need and potential for enhancing oral bioavailability, stability, and processability of drug candidates through appropriate formulation strategies.
• Represents the organization as prime technical contact requiring cross-functional coordination inside and outside the department or company.
• Acts as a technical point of contact, or SME within own group as well as other departments; trains others.
• Leads / supports preparation of CMC regulatory documents.
• Leads initiatives related to continuous improvement or development of new approaches/technologies within or across departments/functions.
• Maintains safety, regulatory, and compliance standards as they relate to the development of pharmaceuticals.
• Prepares / reviews technical reports, batch records, SOPs, publications, and oral presentations as required.

Qualifications & Experience

Required:

• Completed BS in Pharmaceutical Science, Chemical Engineering, or related discipline with 12-15 years of pharmaceutical development experience; MS with 9-12 years of experience; or Ph.D. with 6-8 years of experience.
• Experienced in oral formulation development on multiple projects and for different clinical phases, with hands on experience. 
• Advanced understanding of drug substance, excipients, pharmaceutical unit operations (blending, milling, sieving, granulation, tableting, encapsulatio