Vice President, Health Economics Outcomes Research (HEOR)

The Company

Verve is a clinical-stage genetic medicines company established with a mission to solve the global health epidemic of cardiovascular disease. Founded by world-leading experts in cardiovascular medicine, human genetics and gene-editing, Verve is pioneering a new approach to the care of cardiovascular disease, potentially transforming treatment from chronic management to single-course gene editing medicines. The company’s initial three programs – VERVE-101, VERVE-102, and VERVE-201 – target genes that have been extensively validated as targets for lowering low-density lipoprotein cholesterol (LDL-C), a root cause of cardiovascular disease. VERVE-101 and VERVE-102 are designed to permanently turn off the PCSK9 gene in the liver and are being developed initially for heterozygous familial hypercholesterolemia (HeFH) and ultimately to treat atherosclerotic cardiovascular disease (ASCVD) patients not at goal on oral therapy. VERVE-201 is designed to permanently turn off the ANGPTL3 gene in the liver and is initially being developed for homozygous familial hypercholesterolemia (HoFH) and ultimately to treat patients with refractory hypercholesterolemia. In 2024, Verve was named a Top Place to Work by The Boston Globe for the fourth consecutive year. Verve is headquartered in Boston, Massachusetts.

The Position

The Vice President, Health Economics Outcomes Research (HEOR) will lead the development and execution of health economics outcomes research, real-world evidence strategies, and evidence generation. As a functional expert, this role requires deep cross-functional knowledge to build organizational alignment while anticipating and responding to industry trends. The Vice President will drive strategic initiatives that foster innovation, enhance organizational growth, and have a significant mid- to long-term impact on performance, all while cultivating a high-performance, collaborative culture.

Job Responsibilities

• Serve as a functional expert, understanding cross-functional interactions to build organizational alignment and drive HEOR initiatives, ensuring long-term success and competitiveness.
• Lead the development of economic value propositions within the product development process by working cross-functionally to ensure alignment, developing HEOR strategic plans that integrate key stakeholder input, align clinical and medical priorities.
• Providing thought leadership on access and reimbursement issues to influence new product planning.
• Gather and synthesize insights from payers, key opinion leaders (KOLs), and HEOR experts, staying ahead of scientific and policy trends.
• Offer strategic guidance on clinical trial design, ensuring the selection of relevant endpoints to support HEOR objectives.
• Design and implement research studies that inform portfolio decisions, regulatory submissions, marketing strategies, and reimbursement planning.
• Collaborate with department leaders to address functional challenges and develop effective, forward-thinking solutions.
• Develop and execute optimized pricing and contracting strategies in collaboration with senior leadership.
• Maintain strong partnerships with external agencies and vendors to enhance HEOR capabilities.
• Create a compelling vision that fosters a culture of innovation, high performance, and accountability while promoting diverse perspectives and empowering teams to think creatively in problem-solving and strategy development.
• Prioritize talent development through coaching and mentorship while building and leading high-performing teams that foster collaboration, align career goals with organizational objectives, and break down silos for greater impact.
• Other duties as assigned.

Qualifications

• Education & Experience
  • PhD, Health Services Research, Health Economics, Epidemiology, Public Health, Pharmacy or related field is required.
  • At least 15 years of relevant experience in biotech with deep knowledge of HEOR strategies.
• Skills & Abilities
  • Proven expertise in functional areas with a strong understanding of cross-functional dynamics.
  • Demonstrated ability to develop and implement growth-oriented strategies and initiatives.
  • Advanced strategic thinking skills with a track record of anticipating and responding to industry trends.
  • Strong leadership abilities, fostering high-performance teamwork and a culture of innovation.
  • Excellent interpersonal and communication skills, with the ability to navigate complex organizational dynamics.
  • Experience in talent development and aligning employee career goals with organizational objectives.
  • Strategic mindset and keen intellectual curiosity.

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