Early Development Leader, Oncology R&D

Early Development Leader, Oncology R&D

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.
Find out more:
Our approach to R&D
 

The Early Development Leader (EDL) is a critical role within GSK R&D Oncology which reports to the VP EDLs.  The EDL is the single point of accountability to strategically lead the development of a medicine between Lead Optimization (LO) through Proof of Concept, substantially contributing to defining the early development strategy for an asset.  By working with various stakeholders across R&D, Commercial and Manufacturing, they obtain and manage associated resources and deliver evidence in line with the strategic vision and organizational strategy to support progression beyond early development for a clearly differentiated medicine.

Please note: This position requires an on-site office -based presence 2 to 3 days a week in the Waltham- MA.; UK (London or Stevenage); Upper Providence- PA.; Switzerland (Zug); or Poland (Warsaw).

This role will provide YOU the opportunity to lead key activities to progress YOUR career.  These responsibilities include some of the following:

In this role you will:

Key Responsibilities:

• Strategic leadership and single point of accountability for the development of an asset or portfolio of assets within R&D, from Lead Optimization through Proof of Concept.
• Contributing to and establishing the development strategy aligned with Medicine Profile (MP) with input and alignment from late-stage development, franchise commercial, and medical.
• Makes clear evidence-based go / no go / accelerate decisions, based on whether the results fulfil the strategy set out for the medicine, and identify clear inflection points.
• Identifies and engages the external community appropriately in robust scientific dialogue that generates insight and advances scientific and medical understanding.
• Ensures timely and appropriate interaction and exchange of information between GSK and external communities (e.g., patients, physicians, payers, regulators), in strict adherence with GSK Policies, and GSK Global Scientific Engagement Principles and Standards.
• Ensures balanced and robust scientific communications in all formats.
• Proactively identifies unique regulatory requirements that are necessary for the development of early-stage development e.g. introduction of first dosing in patient populations, clinical pharmacology and metabolism.
• Anticipates the changing healthcare & competitive environment and delivers innovative strategies and plans to generate evidence for relevant pharmacology/efficacy and prescribing/ usage within this environment.
• Understands the impact of new data on the value/positioning of products in guidelines/formularies.
• When necessary, in early stage, partners with Business Development to facilitate diligence reviews, product positioning and/or alternative business strategies (e.g., public private partnerships, co-development) and internal review and decision-making processes in line with GSK governance procedures as well as use of appropriate alliance management mechanisms to ensure successful business transactions and relationships.
• Models GSK values and leadership expectations.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• Bachelor's Degree
• Experience in oncology clinical development
• Experience of early-stage oncology and it’s connections with late-stage development
• Experience of translation of pre-clinical data to develop an oncology clinical development program
• Experience managing and developing individuals and teams to perform to their best strengths
• Experience of preclinical medicine development needs, translati