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Executive Director, Portfolio Strategy & Business Development - OBU Strategy

AstraZeneca
Gaithersburg, United Statesfull_timeVerifiedPosted 19 Mar 2026
💰 $405,332/yr($270,222/yr$405,332/yr)

About the role

Introduction to role:

Drive innovation and impact at AstraZeneca by leading strategy for our industry-leading oncology pipeline. Collaborate with R&D and the Oncology Business Unit (OBU) to shape and deliver cutting-edge therapies that improve patient outcomes and bring us closer to eradicating cancer.

Working with a team of experts across Oncology R&D and the Oncology Business Unit, responsible for creating and implementing strategies to deliver an industry-leading and innovative oncology pipeline that improves patient care and outcomes. Strategies will be multi-brand or brand agnostic and built through analyses, insights, innovative thinking and cross-functional teamwork. An opportunity for a motivated, collaborative data-driven leader to help AstraZeneca one day eradicate cancer as a cause of death. The role

includes people management responsibilities, overseeing a high-performing team and fostering a culture of collaboration, maintaining high-performance and accountability.

Accountabilities:

  • Leads the development and implementation of Business Unit therapy area, multi-brand or brand-agnostic strategies that integrate into one company-wide oncology strategy built with counterparts in global franchises and oncology R&D

  • Drives portfolio strategic initiatives that enhance AZ’s competitiveness and deliver sustainable growth

  • Frequently engages with C-Suite level leaders (SET and SET-1) to provide disciplined insights-driven valuations and strategies

  • Drives clarity and consistency across priority business processes in major governance forums. These include investment decisions, TA Strategy/Portfolio reviews and long range plans across the specific tumour portfolios

  • Engages with Finance VPs to ensure robust assessment of value in annual impairment review (key audit process)

  • Leads the portfolio team in delivery of the commercial analysis, business development valuations, forecasting, market research and insight generation to shape and deliver OBU priorities: R&D decisions, supply planning and TA scenario analysis – including leadership of other team members working across the OBU Strategy team. You will work closely with the tumor area heads in OBU Strategy to do this.

  • Understanding and communication of complex study design, TPPs, CDP’s, combination approaches, competition, pricing, prioritization, and decision making considerations expected in the context of our competitors’ strategies

  • Managing large investment requests and business development opportunity assessments with extreme confidentiality, quality and rigor for consistency in approach

  • Influence with and without authority a large number of senior stakeholders (SET, SET-1, SET-2) across OBU and ORD and criss-crossing tumour and asset alignment meetings

  • Monitor market trends, competitive dynamics, and emerging science to inform strategic planning and business development priorities.

  • Support Head of OBU Strategy to coordinate, oversee and integrate all tumor into one portfolio strategy

  • Collaborate closely with Corporate Development, Finance, and R&D to support deal negotiations and integration planning.

  • Guide and direct team members at the director and associate director level

  • Maintain trusted partnering, credibility and collaboration with clinical, commercial and strategy leaders

Essential Skills & Experience:

  • Bachelor's degree

  • 15 years of relevant industry experience (or MBA/PhD with 10 years of relevant experience)

  • Extensive experience in oncology +/- haematology

  • Strong consultative and communication skills

  • A strong scientific background and strategic analytical skills

  • Industry or consulting experience in pharmaceutical pipeline strategy (market assessment, competitor analysis, forecasting)

  • Excellent analysis and fact-based decision-making

  • Experience with data and/or a science research/bio-pharmaceutical environment

  • Motivated by working in a fast-paced field with clear societal impact

  • Understanding of general business and core marketing principles and application to future healthcare market challenges

  • Familiar with the oncology drug development process and necessary strategic and commercial touch points

  • Prior experience managing direct reports

  • Able to influence without authority and establish and maintain credibility with senior audiences

  • Resourceful, motivated, decisive and proactive; must be able to manage multiple priorities in a fast-growing organization

  • Attention to detail while also a big picture thinker

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Company

AstraZeneca

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