Scientist / Senior Scientist In Clinical Flow Cytometry group

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Scientist / Senior  Scientist: Flow cytometry

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Position Summary

The Clinical Flow Cytometry team within Translational Sciences and Diagnostics organization is seeking a highly motivated Scientist to join our world-class team of flow cytometry scientists. This team is responsible for flow cytometry-based biomarker assays for all phases of clinical studies and trials at BMS. The data generated from this team will influence a broad array of decisions around dose optimization, indication prioritization, and potential drug combinations. In this laboratory-based role, the selected candidate will be responsible for flow cytometry-based biomarker assay development, optimization, qualification/validation, and execution supporting drug programs in various therapeutic areas. The candidate must have strong background in multi-parameter flow cytometry, immunology and translational sciences.

Key Responsibilities:

The chosen scientist will be responsible for:

• Independently design, develop, optimize, validate, and execute novel flow cytometry-based assays for clinical biomarker studies. A high percentage of time will be spent working in the lab.
  • De novo assay design/development will be required.
  • Understanding and practical implementation of flow cytometry assay/ instrument optimization
  • Perform clinical sample analysis as appropriate
  • Execution of assays may be achieved using in-house laboratories, or by working with vendor labs in an outsourcing fashion
• Introduce and troubleshoot new flow cytometry methods and platforms
• Accurate record keeping of experiments and procedures
• Flow cytometry data analysis and interpretation in support of clinical team’s decision making
• Provide technical subject matter expertise to stakeholders in the selection of flow cytometry panels
• Interacting with stakeholders to understand the needs of individual programs, including assay and reportable specifics, timelines, and data delivery needs
• Work with vendor labs to transfer in-house generated assays and oversee/troubleshoot/quality control data generated by external vendors

Minimum Requirements:

• At least 5 years of post-graduate flow cytometry experience in high-dimensional flow, receptor occupancy and functional flow
• Be proficient with flow cytometry analysis software such as Flowjo, FCS Express, OMIQ, etc.
• Must understand flow cytometry data analysis and interpretation
• Understanding of validation principles for flow cytometry assays for clinical trials
• Be proficient in writing method procedures and assay validation and study reports
• Ability to handle multiple projects concurrently, and work in a highly matrixed team
• Must have excellent communication, organization and record keeping skills

Preferred Qualifications:

• Previous industry experience is a plus
• Experience with the BD Biosciences flow cytometers and Cytek Aurora is a plus
• A PhD in a scientific field related to immunology is a plus
• Experience with clinical trial assays or samples  from work with a pharmaceutical company or in a CRO is highly desired.

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