mRNA Drug Product Development Senior Scientist

<p><span>Le contenu du poste est libellé en anglais car il nécessite de nombreuses interactions avec nos filiales à l’international, l'anglais étant la langue de travail.</span><span> </span></p><p><span> </span></p><p><span>This job offer is accessible to all, regardless of gender.</span><span> </span></p><p></p><p><b><span>Job title</span></b><span><span>:</span></span><span> mRNA Drug Product Development Senior Scientist</span></p><ul><li><span>Location:</span><span> Marcy l'Etoile</span><br/> </li></ul><h1>About the job</h1><p></p><p><b>Our Team</b></p><p></p><p><span><span>The mRNA – </span><b><span>Senior </span></b><span><b>Scientist Drug Product Development</b> is part of the Global Drug Product Development (</span><span>G</span><span>DPD) group within the mRNA </span><span>CoE</span><span>. GDPD </span><span>is responsible for</span><span> developing the Drug Product formulation and manufacturing process in support of all ongoing mRNA Vaccine programs within the </span><span>CoE</span><span> from Phase 1 through Phase 3 and commercialization. GDPD achieves this through internal collaborations with our</span><span> </span><span>colleagues in US and through constant collaboration with other departments including Drug Substance</span><span> </span><span>Development, Analytical Sciences, Research, Process Industrialization, Global Process</span><span> </span><span>Harmonization &amp; Tech Transfer, and cGMP Strategic Supply &amp; Operations. GDPD’s mission is to develop</span><span> </span><span>safe, stable, and patient-centric mRNA vaccine and therapeutic Drug Products and associated robust</span><span> </span><span>manufacturing processes.</span></span><span> </span></p><p><span> </span></p><p><b>Main responsibilities:</b></p><ul><li><span><span>Apply scientific </span><span>expertise</span><span> and judgment to </span><span>initiate</span><span>, design</span><span> and </span><span>execute or</span><span> </span><span>supervise execution</span><span> </span><span>of </span><span>the</span><span> development of liquid and lyophilized mRNA-LNP drug product</span><span> </span><span>formulation and process</span></span></li><li><span><span>Make scientific presentations and report project progress within mRNA CoE</span><span> Formulation teams and with partners and in international forums</span></span></li><li><span><span>As a Subject Matter Expert in drug product development, </span><span>be an impactful contributor </span><span>to p</span><span>roje</span><span>ct teams and actively </span><span>participate</span><span> </span><span>in DP sub-teams</span></span></li><li><span><span>Provide consolidated</span><span> DP development technical work packages with timelines, </span><span>resources</span><span> and critical path activities</span></span></li><li><span><span>Drive organizational goal of rapidly incorporating innovative advances in drug product platform (thermostable formulations and process improvements)</span></span></li><li><span><span>Promote innovation, state</span><span> of the art technologies, and propose strategies using publications to improve the products</span></span></li><li><span><span>Proactively collaborate with other functions to meet projects and platform</span><span> milestones</span></span></li><li><span><span>Proactively collaborate with other groups or sites in transfer of information, materials</span><span> and</span><span> </span><span>drug</span><span> </span><span>product technology</span></span></li><li><span><span>Promote internal assessment of new DP technologies and scientific network to leverage</span><span> internal </span><span>and external </span><span>expertise</span></span></li><li><span><span>Make decisions that require developing new options to solve moderately complex problems</span></span></li><li><span><span>Demonstrate continuous growth in depth and breadth of personal scientific knowledge and<span> </span>understanding of strategic goals of group, team, and company</span></span></li><li><span><span>Maintain a consistent record of publications, patents, external presentations</span></span></li><li><span><span>Proactively participate</span><span> in laboratory organization</span><span> </span><span>(including HSE, quality aspects) </span><span>and continuous improvement of WoW</span></span></li><li><span><span>Supervise lab activities with technicians</span><span>, internships</span><span> and </span><span>TPW</span><span> (in</span><span>direct repo</span><span>rt)</span><span>, when appropriate</span></span></li></ul><p></p><p><b>About your development opportunities</b><br/> </p><p>In this role, you will gain a technical understanding of mRNA vaccine drug product development, drug product characterization techniques, and process development study design strategies. You will be exposed to, and gain an understanding of, what other technical function are responsible for and how they all play a role in mRNA vaccine development. You will have the opportu