Research Scientist III - Immunoassay Development

Would you like to join an international team working to improve the future of healthcare? Do you want to enhance the lives of millions of people? Grifols is a global healthcare company that since 1909 has been working to improve the health and well-being of people around the world. We are leaders in plasma-derived medicines and transfusion medicine and develop, produce and market innovative medicines, solutions and services in more than 110 countries and regions.

Summary

The Immunoassay Research and Development group at Grifols Diagnostic Solutions in Emeryville, CA is seeking a experienced immunoassay development scientist to help develop ultrasensitive assays for multiple commercial indications.

 

Research Scientist III will lead and perform innovative research and work collaboratively with other scientific team members within R&D to design, develop, and verify immunoassays. This scientist will initiate, execute, and interpret scientistic research projects pertaining to immunoassay development, such as ELISA and/or other proprietary immune platforms. This scientist will work cross functionally with technical teams within and outside of R&D. This scientist will mentor or manager junior technical staff in pursuit of better and more sensitive immunoassays.

 

Come join a vibrant immunoassay development team and have a direct impact on human health!

 

Primary Responsibilities

• Plans multifaceted projects and incorporates multiple experimental approaches appropriately.
• Leads and carries out immunoassay design, development, and validation using novel and commercial recombinant proteins for multiple indications and commercial applications.
• Leads selection and bioconjugation of recombinant proteins to develop reagents and tools for immunoassays.
• Evaluates protein stability, stoichiometry, and purity using modern analytical techniques and develops protein, reagent and assay formulations.
• Develops assay product prototypes for multiple indications and transfers them to process development and manufacturing teams.
• Independently or with team members, plans R&D projects requiring initiative and judgement within defined procedures and practices.
• Independently selects methodological approaches and specific methods to achieve project objectives. 
• Exercises judgment and initiative in making research project decisions.  Performs experiments in the laboratory, as needed.
• Identifies, analyzes, and interprets project results. Communicates results and project status to key stakeholders and management. 
• Clearly communicates results and project status to key stakeholders and management in a manner that's tailored to diverse audiences.  
• Sources and interprets literature and runs database searches to aid in designing experimental studies, troubleshooting experiments, and interpreting findings. Writes original proposals for research projects and remains current on pertinent scientific topics. 
• Works cross functionally and leads collaborations within and outside of R&D, external partners, and/or CROs. 
• Prepares written reports on all phases of laboratory experimental projects.
• Authors or co-authors scientific papers and /or journal articles and technical reports. 
• Reviews and edits pertinent regulatory documents. 
• Prepares and defends patent disclosures and applications.
• May mentor, train or manage other R&D technical staff.
• Attends and participates in scientific meetings, seminars and leadership team meetings.
• Partners and collaborates with small teams in a scientific development environment.
• Plan and prioritize activities while anticipating risks and challenges, monitor progress, and deliver projects to meet timelines and milestones

 

Knowledge, Skills, and Abilities

• Background in protein biochemistry, structual biology, or protein biophysics
• Subject matter expert in immunoassay development and validation, including antibody development and screening, ELISA, western blot, immunostaining, BLI
• Experience with DOE for buffer formulation and relevant sofrware packages
• Experience bringing tests for FDA and/or EU approval is a plus
• Experience in method development and optimization of an