Senior Scientist, Biology-Discovery

Job Description

We’re seeking an experienced Senior Scientist to join the Infectious Disease and Vaccines department at our research site in West Point, PA. The candidate will have a primary role on a team responsible for the discovery and development of novel antiviral treatments, with a particular focus on HIV. The candidate will independently design and execute experiments to interrogate fundamental virus biology, virus-host interactions, and immunological responses using various biochemical and cell-based assays and in vivo disease models. The candidate should have a strong background in virology, immunoassay and genomic technologies, cell biology, animal pharmacology, and general knowledge of infectious disease drug development and T cell biology. We value creative-thinking, teamwork, and independent analytical problem solving. If you are a highly motivated team player with a strong desire to impact basic research and translational medicine, we invite you to consider joining our team.

EDUCATION REQUIREMENT:

BS/BA degree in Biology or Biomedical Sciences with a minimum 9 years of experience in industry and/or academia, or a MS degree in Biology or Biomedical Sciences with 6 years of experience in industry and or academia, or PhD with >1 year postdoctoral experience.

REQUIRED SKILLS:

• Proficiency in HIV biology, including latency, and demonstrated rigorous productive research in investigative viral replication, virus-host interactions, innate and adaptive immunity, and HIV pathogenesis.

• Highly skilled in virology with expertise in a range of virological, molecular and cellular techniques, including in vitro and in vivo disease models.

• Proven track record in immunological and molecular techniques, including cell culture and T-cell purifications, virus production, ELISA, flow cytometry, PCR, and has experience with animal pharmacology.

• Knowledgeable in drug discovery and translational research.

• Good communication (verbal & writing) skills with a track record of publications.

• Solid computer skills, independent experimental design and execution, analytical problem-solving capabilities, and ability to work collaboratively in a multi-disciplinary team environment.

• Keen awareness of emerging biology and new technologies.

PREFERRED SKILLS:

• Multi-parameter Flow cytometry and ICS. Experience with instruments including BD Symphony, LSR II, and FACSARIA and Sony SH800 desirable.

• Knowledge of biomarker discovery and assay development as it relates to infectious diseases and immune responses, particularly 10X genomics or other immuno-profiling platform experience.

• In vitro and ex-vivo probing of tissues for host-pathogen responses using biochemical methods, cell-based assays, and in vivo disease models, particularly for infectious disease.

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