Senior/ Staff Bioprocess Engineer, Cell Production & Process Development (OMG)

California, US residents click here.

The job details are as follows:

Who we are

We are the first publicly-traded biotech or pharmaceutical company to take the form of a public benefit corporation. Our public benefit purpose is to provide a brighter future for patients through the development of novel pharmaceutical therapies; and technologies that expand the availability of transplantable organs.

United Therapeutics (Nasdaq: UTHR) seeks to travel down the corridors of indifference to develop treatments for rare, deadly diseases. We were founded in 1996 by a family seeking a cure for their daughter’s pulmonary arterial hypertension( PAH). Today, we have six FDA-approved therapies that treat PAH, pulmonary hypertension associated with interstitial lung disease (PH-ILD) and neuroblastoma, a rare pediatric cancer. Our near-term pipeline seeks to develop additional therapies for PAH and pulmonary fibrosis (PF).

The cure for end-stage life-threatening diseases like PAH, PH-ILD, PF, and many others is an organ transplant, but only a small percentage of donated organs are available to address the vast need. For this reason, we are working to create bio-artificial organs to address the shortage of kidneys, hearts, lungs, and livers available for transplant. We believe an unlimited supply of tolerable, transplantable organs will eliminate the transplant waiting list and cure end-stage organ diseases for which transplant is not currently an option.

Who you are:

We are looking for our iPSC wizard who loves production.  The SR or Staff Bioprocess Engineer, Cell Production and Process Development (OMG) will be responsible for leading sub-projects focused on scaling up and developing robust, GMP-compliant methods to produce iPSC-derived autologous cells for 3D printed organs. We are pushing every boundary of what we thought was possible in science with all of the support  and cutting edge tech possible. Interested? We don’t blame you – apply below.

Minimum Requirements Senior Level:

• 5+ years of relevant experience in stem cell therapy, bioreactor cell production, scale up, regenerative medicine, tissue engineering with a BA/BS Degree in biomedical science, cell biology or related field OR 3+ years of relevant experience in stem cell therapy, bioreactor cell production, scale up, regenerative medicine, tissue engineering with a Master's Degree in biomedical science, cell biology or related field
• Strong background in cellular process development
• Technical expertise in cell bioreactor culture, preferably Sartorius Ambr/B-DCU systems and/or vertical wheel bioreactors with scales up to 10L+
• Proficient with appropriate word processing, spreadsheet, presentation, and related standard software
• Experience with laboratory instrumentation and data software
• Ability to accommodate a non-traditional work schedule (e.g. Sun-Thu, Tue-Sat)

Preferred Requirements Senior Level:

• Experience with automated cell processing equipment, such as CliniMACS Plus, LOVO, Cue, Sepax, Sefia, Rotea
• Knowledgeable in the transfer of R&D cell expansion methods to GMP
• Experience with relevant statistical software (GraphPad Prism, MODDE, SIMCA, JMP, etc.)
• Previous industry experience
• Experience IPSC Culturing and Differentiating

Minimum Qualifications Staff Level:

• 8+ years of relevant industry experience with prior experience in stem cell therapy, bioreactor cell production scale up, regenerative medicine, tissue engineering with a BA/BS Degree in biomedical science, cell biology or related field OR 6+ years of relevant industry experience with prior experience in stem cell therapy, bioreactor cell production scale up, regenerative medicine, tissue engineering with a Master's Degree in biomedical science, cell biology or related field OR 2+ years of relevant industry experience with prior experience in stem cell therapy, bioreactor cell production scale up, regenerative medicine, tissue engineering with a PhD in biomedical science, cell biology or related field
• Technical expertise in cellular process development
• Technical expertise in cell bioreactor culture, preferably Sartorius Ambr/B-DCU systems and/or vertical wheel bioreactors with scales up to 10L+
• Knowledge/Experience in transfer of R&D cell expansion methods to GMP
• Proficient with appropriate word processing, spreadsheet, presentation and related standard software; Experience with laboratory instrumentation and data software. Experience with relevant statisti