Senior Scientist II, Biologics Purification

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

Join AbbVie’s Biologics Discovery Sciences group and make a tangible impact in advancing innovative biologic therapies. As a scientist specializing in Biologics Purification, you will play a pivotal role in driving drug discovery, collaborating within a dynamic team dedicated to supporting transformative science that improves patient lives worldwide. Your expertise will help deliver high-purity bispecific antibody-based biologic candidates with suitable purity/characteristics to support the advancement of vital in vitro (i.e. drug-like property assays, binding, cell-based assays, etc.) and in vivo studies (i.e. efficacy, non-GLP NHP PK, DRF, etc.). 

Key Responsibilities:

• Lead the purification of bispecific antibody biologics to support critical research assays and studies
• Design and execution of robust process development strategies necessary to address production liabilities which factor into future process scalability. 
• Apply advanced bioprocessing and chromatography techniques at large scale
• Utilize in silico tools, DOE methodologies, and predictive modeling to optimize protein separation and maximize yield/quality
• Integrate and manage analytical data using LIMS, ETL tools, and data extraction APIs
• Collaborate with multidisciplinary teams, translating molecular insights into functional results
• Stay current with emerging scientific literature to foster innovation and continuous improvement
• Present findings clearly to diverse audiences and document results with rigor

Qualifications

• BS, MS, or PhD in Bioinformatics, Biophysics, Chemical Engineering, or related field with typically 12+ years (BS), 10+