Upstream Development Associate

Company Description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years.

Job Description

The Upstream Development Associate will support the design and execution of laboratory-based studies focused on upstream process development. This role will contribute to the optimization and scale-up of processes to support the production of biologics. The engineer will collaborate with cross-functional teams and assist in the transfer of processes to external partners and internal manufacturing groups.

Responsibilities Include: 

• Perform upstream process operations, including cell banking, cell expansion, bioreactor runs, process optimization, and characterization.
• Collaborate with team members and cross-functional groups to carry out upstream studies using shake flasks, wave bags, and benchtop bioreactors.
• Utilize high-throughput systems such as AMBR15, AMBR250, and Robocolumns, along with analytical tools like cell counters and bioanalyzers to support experimental work.
• Coordinate sample submissions with the testing team, organize and analyze data using tools like Microsoft Excel, JMP, and Spotfire, and summarize key findings.
• Maintain accurate and timely documentation of lab work in electronic lab notebooks and assist in the preparation of technical reports.

Qualifications

Minimum Qualifications: 

• Bachelor’s degree in chemistry, biology, pharmacy, engineering, or a related field with 2–4 years of relevant industry experience; or
• Bachelor’s degree in engineering or a related discipline with 0–2 years of relevant experience; or
• Master’s degree in a related scientific or engineering field with 0–2 years of relevant experience
• Hands-on experience in a biologics laboratory or GMP manufacturing environment
• Familiarity with mammalian cell culture and aseptic techniques
• Experience operating bench-scale bioreactors and related equipment, including:
  • Metabolite analyzers
  • Shake flasks
  • Cell culture plates
• Authorization to work in the United States indefinitely without restriction or sponsorship

The Ideal Candidate will have: 

• Experience with harvest filtration and chromatography techniques
• Background in optimizing upstream processes or expression systems
• Familiarity with advanced analytical tools and bioreactor technologies
• Ability to troubleshoot complex issues and resolve routine technical challenges
• Strong verbal and written communication skills
• Ability to be highly organized, detail-oriented, and self-motivated

Additional Information

This position is Full-Time, Monday-Friday, 8:00 a.m. - 5:00 p.m. with overtime as needed and the potential for some off-shift hours as depending on the project. Candidates living within a commutable distance of Lexington, MA, are encouraged to apply.

Excellent full-time benefits include: 

• comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins Lancaster Laboratories Professional Scientific Service