Sr. Scientist, Analytical R&D (Onsite)

Job Description

Our Scientists are our Inventors. We deliver robust scientific data and interpretation that drives the commercialization of breakthrough therapeutics using innovative thinking, state-of-the-art facilities and modern equipment. Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of people like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing your career.

The Analytical Research and Development organization in West Point, PA is seeking a motivated scientist with technical expertise in mass spectrometry-based protein, protein conjugation or oligonucleotides or polysaccharide characterization. In addition to mass spectrometry skills, we are also seeking candidates with strong proteomics and data science skills.

The successful candidate is expected to independently conduct mass spectrometry experiments to support multiple vaccines programs, represent the team in cross-functional teams and develop new methods to solve current industry challenges. The work requires documenting experiments in electronic laboratory notebooks, authoring summaries to inform stakeholders, as well as presenting at seminars and publishing in scientific journals. The candidate with the right skills will also participate in optimizing our sample preparation, data processing and reporting strategies.

Primary Responsibilities

• Perform LC-MS based assays including peptide mapping, intact mass, native mass spectrometry, proteomics, hydrogen deuterium exchange (HDX) and host cell protein analysis or oligonucleotides or polysaccharide characterization for vaccines programs.

• Represent the mass spectrometry group in project teams.

• Author technical reports and scientific presentations.

• Explore and develop new technologies applicable to our field.

• Perform data processing with Genedata or other biopharma data interpretation software.

• Demonstrate effective multitasking, prioritization and problem-solving skills in the planning and execution of experiments.

Education Requirements

• Ph.D. in Analytical Chemistry or Biological Sciences in the field of mass spectrometry

• Candidates with a MS degree and 4+ years, or BS degree and 7+ years of relevant experience will also be considered.

Required Experience and Skills

• Experience conducting mass spectrometry and proteomics experiments, including sample preparation and optimization, mass spectrometer operation and maintenance, and data interpretation and analysis.

• Experience with Thermo and Waters instruments.

• Excellent verbal and written communications skills, as demonstrated through high impact scientific publications and presentations. 

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Preferred Experience and Skills

• Experienced in hydrogen deuterium exchange (HDX)

• Familiarity with electronic laboratory notebook applications and good documentation practices.

• Good understanding of vaccines development.

• Familiarity with Genedata or other biopharma MS software.

• Experience characterizing vaccines or recombinant proteins.

• Experience with protein conjugation, oligonucleotides, or polysaccharide characterization.

• Familiarity with R programming language for data processing, statistics and visualization.

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As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected <