Executive Director, Medical Affairs (East)

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics. 

Why Join Our Medical Affairs Team? 

• Innovative Environment: Join the global leader in precision cancer immunotherapy and help drive the launch of our first PRAME-targeted therapy, anzu-cel. Your work will directly support a team at the forefront of scientific and clinical breakthroughs. 

• Collaborative Culture: You will be part of a diverse and agile team that values your initiative, discretion, and ability to enable team productivity and growth. 

• Global Impact: Support a mission that extends far beyond the office. At Immatics, your expertise helps accelerate therapies that target more than 50 cancers, improving outcomes for patients worldwide. 

Position Overview: 

The Executive Director, Medical Affairs (East), is a seasoned medical affairs leader with 

oncology/hematology expertise, strong business acumen, and an established history of shaping medical strategy and driving medical launch readiness and execution in the US market. 

The ideal candidate will have robust experience working in close partnership within a highly functioning, matrix team. He/she will be an integral part of the Medical Affairs leadership team and will partner closely with the Executive Director, Medical Affairs (West) to ensure nationwide alignment, operational excellence, and consistent field impact. This individual will directly manage and develop the Eastern US MSL field team. Areas of focus include developing field medical strategy guiding the field medical team's externally facing activities, coordinating/executing engagements with external stakeholders, supporting publications strategy, and representing the field medical team (East), both internally and externally, to support ongoing pipeline development. 

The Executive Director, Medical Affairs (East) will also provide leadership and oversight for Patient Advocacy strategy and partnerships, ensuring strong collaboration with internal and external partners to advance patient-focused initiatives. 

FLSA Classification: Salary, Exempt 
Schedule: 8:00 AM – 5:00 PM; Monday to Friday; Remote 
Reports to: Vice President, Medical Affairs  
Location: Fully Remote  

What You’ll Do: 

Team Leadership & Development 

• Establish and lead the Eastern region of MSLs, including recruitment, onboarding, and performance development.  

• Manage a geographically dispersed team covering the Eastern half of the US, ensuring consistent, high-quality scientific engagement and field execution. 

• Build a culture of scientific excellence, accountability, and collaboration aligned with Immatics’ mission. 

• Ensure the team operates in compliance with internal SOPs, company standards, and regulatory requirements. 

• Provide coaching, mentorship, and performance management to ensure MSL effectiveness and growth. 

Strategic Field Execution 

• Translate Medical Affairs objectives into clear field medical strategies that enhance scientific exchange, trial support, and data generation activities. 

• Guide MSL engagement with investigators, opinion leaders, and treatment centers to support trial execution, insights capture, and regional education. 

• Drive regional readiness and scientific fluency for launch and pipeline programs, ensuring alignment with overall US strategy. 

• Oversee field medical coverage for national and regional congresses ensuring seamless pre-, on-site, and post-congress execution. 

• Ensure external scientific interactions are conducted in a compliant and balanced manner. 

Pre-Launch & Launch Readiness 

• Drive regional execution of launch readiness for TCR T-cell therapy programs, including scientific education, stakeholder mapping, and insights integration. 

• Partner with cross-functional teams to ensure consistent launch messaging and field preparedness