Manager, Production; Manufacturing

Manager, Production Operations in Springfield, MO (Night shift)

Build your future at Curia, where our work has the power to save lives

Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives.

We proudly offer

•    Generous benefit options (eligible first day of employment) 
•    Paid training, vacation and holidays (vacation accrual begins on first day of employment)
•    Career advancement opportunities 
•    Education reimbursement
•    401K program with matching contributions
•    Learning platform
•    And more! 

The Production Operations Manager is a key driver of safety, quality, compliance, and operational excellence within Curia’s cGMP manufacturing environment. Partnering closely with the Associate Director of Production, this role oversees Production Supervisors and helps ensure consistent execution of manufacturing activities across shifts. The Production Operations Manager establishes clear expectations, develops leaders, addresses performance and operational challenges, and promotes accountability throughout the Production organization.  From strengthening procedures and implementing best practices to developing employees and monitoring meaningful performance metrics, this position helps build a Production department that performs at a high standard every day. Through strong leadership and cross-functional collaboration, the Production Operations Manager helps ensure every batch is manufactured safely, compliantly, efficiently, and with the quality our customers and patients depend on.

The ideal candidate is a collaborative and visible leader who enjoys developing people, improving systems, and solving complex operational problems. This individual uses data, practical cGMP knowledge, and effective communication to identify root causes and implement sustainable improvements in safety, quality, compliance, and operational performance.

Essential Responsibilities

Leadership & Team Development

• Lead, coach, and develop Production Supervisors, establishing clear expectations and consistent practices across shifts and operating areas.

• Hold supervisors accountable for safety, quality, compliance, schedule execution, employee performance, training, documentation, and timely escalation of concerns.

• Support supervisors in addressing staffing, attendance, performance, conduct, and employee-relations matters in partnership with Human Resources.

• Evaluate team capabilities, identify development needs, and develop plans to strengthen leadership effectiveness and operational readiness.

• Foster a culture of accountability, engagement, collaboration, continuous learning, and shared ownership of safety and quality.

Operational Leadership

• Oversee daily Production activities and work with supervisors to ensure appropriate staffing, work assignments, communication, and execution of the production schedule.

• Monitor department performance using safety, quality, compliance, productivity, and schedule-attainment metrics; identify trends and implement improvements.

• Serve as an escalation point for operational, staffing, safety, quality, and compliance issues, ensuring concerns are resolved or elevated promptly.

• Participate in production planning and partner with the Associate Director of Production on department priorities, staffing, resource allocation, and organizational needs.

• Provide backup operational, payroll, and timekeeping support during planned or unplanned Production Supervisor absences.

• Ensure facilities, equipment, processes, and employees operate safely and in accordance with applicable requirements.

Quality, Compliance & Continuous Improvement

• Ensure Production activities and documentation comply with cGMP, GDP, approved procedures, batch records, and applicable regulatory requirements.

• Lead or support investigations, root cause analyses, deviations, CAPAs, change controls, and validation activities, ensuring actions are completed thoroughly and on time.

• Author, review, revise, and approve Production SOPs, work instructions, master batch records, and other controlled documents.

• Standardize procedures and operating practices to improve consistency across shifts and strengthen safety, quality, compliance, and operational performance.

• Maintain department readiness for