Principal Scientist - Biomarker Assay Development - Translational Research

About the Department                                                                                                                                               

Our Research & Development organization brings together the best minds in life science innovation. The teams located in facilities in Lexington, Watertown, Cambridge and Seattle reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. Our R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources, and stability, uniting the best of both worlds to develop new medicines for patients.

 

The Position

The Principal Scientist will lead the scientific efforts in developing biomarker assay strategies, qualifying new biomarker assays (LBA, flow cytometry), and introducing innovative technological platforms and methods for biomarker quantification. This will involve serving as a subject matter expert, offering strategic guidance on assays and technology to project teams, and initiating and leading strategic scientific and technological partnerships within the biomarker assay field. Additionally, the Principal Scientist may provide mentorship and training to colleagues at various levels within the Biomarker Assay Development department, and will represent the organization in the external scientific community through impactful research publications and presentations.

 

Relationship

Reports to the Director Biomarker Assay Development. Internal relationships include working closely with technical staff and other members of the Biomarker Assay Development department (in the US and Denmark); regular collaborations with members of other research departments at GNAT, GDD and GRT; frequent interaction with project managers and other colleagues across global R&D. Individual may indirectly supervise colleagues at various levels.  
Individual will interact with external research collaborators both academia- and industry-based

 

Essential Functions

• Independently handle complex tasks requiring specialized knowledge crucial to biomarker assay development, while understanding the relationship between scientific project objectives and long-term business needs.
• Demonstrates established depth and/or breadth expertise biomarker assays, and be able to provide strong technical guidance within the field of biomarker assay development .
• Leads or supervises multiple biomarker assay strategies concurrently, and is accountable for planning execution, and delivering, including setting strategy goals and timelines.
• Develop, plan, and execute biomarker assay strategies for the development and qualification of assays for TE biomarkers, PoM biomarkers, and disease modulation-associated biomarkers.
• Maintain a comprehensive understanding of theoretical knowledge and stay connected to the external scientific community through ongoing assessment of relevant literature. 
• Propose new projects that align with the strategic agenda and address gaps in technological capabilities.
• Actively participate in virtual global team meetings.
• Establish, lead, and maintain professional networks internally and externally, identifying opportunities for academic/industrial collaboration and co-creation
• Serve as the organization's representative by externally communicating impactful scientific research through presentations at external conferences, and by publishing in scientific journals and patents
• Provides significant mentorship and training of junior and senior colleagues.

 

Qualifications

• Master’s degree with 12+ years of relevant experience, or PhD with 8+ years of relevant experience required